Document Detail

Low tissue gastrin content in the ovine distal duodenum is associated with increased percentage of G34.
MedLine Citation:
PMID:  8097147     Owner:  NLM     Status:  MEDLINE    
1. In adult sheep and in lambs, over 95% of gastrin in the abomasal antrum was G17 with small amounts of G34 and lesser amounts of Component I. 2. Low gastrin concentration in the proximal duodenum was associated with a reduced percentage of G17. 3. The proportion of G34 increased progressively down the duodenum from a mean of 7% proximally to 47% in the most distal segment, and correlated negatively in any segment with the gastrin content. 4. In both the antrum and proximal duodenum, 60-70% of the G17 was in the sulphated form. 5. The gastroepiploic venous serum contained less G17 and more G34 than the tissues and up to 19% G14.
H V Simpson; G W Reynolds; D H Carr
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Comparative biochemistry and physiology. Comparative physiology     Volume:  104     ISSN:  -     ISO Abbreviation:  Comp. Biochem. Physiol. Comp. Physiol.     Publication Date:  1993 Mar 
Date Detail:
Created Date:  1993-05-18     Completed Date:  1993-05-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9441449     Medline TA:  Comp Biochem Physiol Comp Physiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  461-8     Citation Subset:  IM    
Department of Physiology and Anatomy, Massey University, Palmerston North, New Zealand.
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MeSH Terms
Aging / metabolism
Chromatography, Gel
Chromatography, Ion Exchange
Duodenum / drug effects,  metabolism*
Gastrins / blood,  metabolism*
Intestinal Mucosa / metabolism
Protein Precursors / blood,  metabolism*
Pyloric Antrum / metabolism
Sulfates / metabolism
Reg. No./Substance:
0/Gastrins; 0/Protein Precursors; 0/Sulfates; 53988-98-0/big gastrin; 60748-06-3/gastrin 17

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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