Document Detail

Low resting energy expenditure in middle-aged and elderly hemodialysis patients with poor nutritional status.
MedLine Citation:
PMID:  16537994     Owner:  NLM     Status:  MEDLINE    
Due to high resting energy expenditure (REE) in maintenance hemodialysis patients, an increase in energy intake is usually recommended to improve their nutritional status. However, some patients appear to have poor appetite and low energy intake. In such patients low energy metabolism is expected. We hypothesized that in maintenance hemodialysis patients there are two types of the energy metabolism, high and low. This study was aimed at finding the energy metabolism in maintenance hemodialysis patients, especially in those with poor nutritional status. Subjects were hemodialysis out-patients (34 males and 20 females, mean age 59.1+/-10.7 y). REE was measured by an indirect calorimeter. Protein intake was obtained from normalized protein catabolic rate (nPCR), and physical activity level (PAL) was obtained by time study. Nutritional status assessed by serum albumin concentration was poor (3.7+/-0.2 g/dL) in spite of the adequate protein intake (1.1+/-0.3 g/kg per day). Only 11% of the subjects had appropriate serum albumin concentration. Mean REE was 24.6 kcal/kg per day which was lower than that of healthy Japanese (26.5 kcal/kg per day). REE and PAL positively correlated with serum albumin concentration (p<0.01). The results suggest that maintenance hemodialysis patients with poor nutritional status may have low REE.
Miho Kogirima; Katsuhiko Sakaguchi; Kohsuke Nishino; Yoko Ichikawa; Fumie Hiramatsu; Shigeru Yamamoto
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The journal of medical investigation : JMI     Volume:  53     ISSN:  1343-1420     ISO Abbreviation:  J. Med. Invest.     Publication Date:  2006 Feb 
Date Detail:
Created Date:  2006-03-15     Completed Date:  2006-05-25     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  9716841     Medline TA:  J Med Invest     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  34-41     Citation Subset:  IM    
Department of Food Science and Nutrition, Doshisha Women's College, Kyoto, Japan.
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MeSH Terms
Basal Metabolism*
Energy Intake
Middle Aged
Nutritional Status*
Renal Dialysis*
Serum Albumin / metabolism
Reg. No./Substance:
0/Serum Albumin

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