Document Detail

Low prevalence of juvenile-onset Behcet's disease with uveitis in East/South Asian people.
MedLine Citation:
PMID:  19666928     Owner:  NLM     Status:  MEDLINE    
AIM: There is little information on the demographic and clinical characteristics of Behçet's disease in children in different parts of the world. We sought to provide this information through a questionnaire survey of specialist eye centres. METHODS: Descriptive questionnaires were collected from 25 eye centres in 14 countries. The questionnaire surveyed details of juvenile-onset Behçet's disease with uveitis. Ethnic groups, clinical features, treatments and prognosis of paediatric-age Behçet's disease were examined on a worldwide scale. RESULTS: The clinical data of 135 juvenile-onset and 1227 adult-onset patients with uveitis were collected. The average age of disease diagnosis in the children was 11.7 years old. Of the ethnic groups identified 54% were from Middle East, 43% from Europe, but only 2% from East/South Asian countries. By contrast, 19.2% of adult patients were from East or South Asia. The frequency of genital ulcers in juvenile patients was 38.7%, which was significantly lower than in adult cases (53.5%; p<0.01). CONCLUSIONS: Behçet's disease with uveitis was less common in children than in adults in East/South Asia. Although the clinical features of the systemic disease were similar in children and adults, there was a lower frequency of genital ulceration in children.
N Kitaichi; A Miyazaki; M R Stanford; D Iwata; H Chams; S Ohno
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-08-09
Journal Detail:
Title:  The British journal of ophthalmology     Volume:  93     ISSN:  1468-2079     ISO Abbreviation:  Br J Ophthalmol     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-10-26     Completed Date:  2009-12-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0421041     Medline TA:  Br J Ophthalmol     Country:  England    
Other Details:
Languages:  eng     Pagination:  1428-30     Citation Subset:  IM    
Department of Ophthalmology and Visual Sciences, Hokkaido University Graduate School of Medicine, Sapporo 060-8638, Japan.
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MeSH Terms
Age of Onset
Asia, Southeastern / ethnology
Behcet Syndrome / epidemiology,  ethnology*
Europe / ethnology
Far East / ethnology
Middle East / ethnology

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