Document Detail

Low prevalence of erosive esophagitis and Barrett esophagus in a tertiary referral center in Turkey.
MedLine Citation:
PMID:  19115148     Owner:  NLM     Status:  MEDLINE    
BACKGROUND/AIMS: The purpose of upper gastrointestinal endoscopy in gastroesophageal reflux disease is to detect the complications; both Barrett esophagus and erosive esophagitis are common in developed countries. We aimed to investigate the ratio of esophageal complications in gastroesophageal reflux disease and the relationship between reflux symptoms and erosive esophagitis. METHODS: Six hundred forty-five consecutive adult patients presenting to the Reflux Outpatient Clinic were evaluated prospectively. One hundred sixty patients who underwent upper gastrointestinal endoscopy and who complained of heartburn or regurgitation occurring at least weekly were selected. The complaints and general features of patients were queried via a detailed questionnaire. RESULTS: Twenty-seven patients (17%) had endoscopic evidence of erosive esophagitis. Barrett esophagus was found in 3 patients (2%). Neither esophageal stricture nor adenocarcinoma was found. Esophagitis was low grade (grades A and B) in 25 of the 27 (92%) with erosive esophagitis. Patients with erosive esophagitis consumed less alcohol than patients with non-erosive reflux disease. No difference was found between the severity of symptoms in patients with erosive esophagitis and non-erosive reflux disease. CONCLUSIONS: Barrett esophagus and erosive esophagitis were less common compared to the literature although the study was conducted in a tertiary reference center for gastroesophageal reflux disease. The presence of severe symptoms in gastroesophageal reflux disease is not an indication for upper gastrointestinal endoscopy. No impact of Helicobacter pylori on the severity of esophagitis or symptoms was shown.
Berna Bayrakçi; Elmas Kasap; Gül Kitapçioğlu; Serhat Bor
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology     Volume:  19     ISSN:  1300-4948     ISO Abbreviation:  Turk J Gastroenterol     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-12-30     Completed Date:  2009-04-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9515841     Medline TA:  Turk J Gastroenterol     Country:  Turkey    
Other Details:
Languages:  eng     Pagination:  145-51     Citation Subset:  IM    
Department of Gastroenterology, Ege University, School of Medicine, Izmir, Turkey.
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MeSH Terms
Barrett Esophagus / epidemiology*,  etiology,  pathology
Chi-Square Distribution
Esophagitis / epidemiology*,  etiology,  pathology
Gastroesophageal Reflux / complications,  diagnosis,  epidemiology
Middle Aged
Prospective Studies
Turkey / epidemiology
Comment In:
Turk J Gastroenterol. 2008 Sep;19(3):143-4   [PMID:  19115147 ]

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