| Low peritoneal and systemic inflammatory response after laparoscopy-assisted gastrectomy compared to open gastrectomy. | |
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MedLine Citation:
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PMID: 21661448 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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BACKGROUND/AIMS: Peritoneal immune response as well as systemic response was objectively evaluated in laparoscopy-assisted distal gastrectomy (LADG) compared to open distal gastrectomy (ODG). METHODOLOGY: A total of 42 patients with gastric cancer were enrolled, with 23 undergoing LADG and 19 ODG. We evaluated the levels of IL-6 in peritoneal drain fluid, serum C-reactive protein (CRP), white blood cells (WBC), and the postoperative presence of systemic inflammatory response syndrome (SIRS). RESULTS: The serum CRP level was significantly higher in the ODG group than in the LADG group (p=0.007) on postoperative day (POD) 1. WBC counts showed no statistically significant difference between the two groups (p=0.105). The rate of cases exhibiting SIRS was significantly higher in the ODG group than in the LADG group (p<0.001). The IL-6 level of drain fluid was significantly higher in the ODG group than the LADG group (p<0.01) on POD1. Although weak correlation between IL-6 on POD1 and blood loss (R=0.38, p=0.0154) was observed, no significant correlation between IL-6 and operation time was noted. CONCLUSIONS: LADG seems to be a lesser traumatic approach for the treatment of gastric cancer. |
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Authors:
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Toshiyuki Natsume; Hiroshi Kawahira; Hideki Hayashi; Yoshihiro Nabeya; Takashi Akai; Daisuke Horibe; Kiyohiko Shuto; Yasunori Akutsu; Kazuyuki Matsushita; Fumio Nomura; Hisahiro Matsubara |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Hepato-gastroenterology Volume: 58 ISSN: 0172-6390 ISO Abbreviation: Hepatogastroenterology Publication Date: 2011 Mar-Apr |
Date Detail:
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Created Date: 2011-06-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8007849 Medline TA: Hepatogastroenterology Country: Greece |
Other Details:
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Languages: eng Pagination: 659-62 Citation Subset: IM |
Affiliation:
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Department of Frontier Surgery, Chiba University Graduate School of Medicine, Chiba, Japan. tnatsu22@faculty.chiba-u.jp |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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