| "Low perfusion hyperemia" following middle cerebral arterial occlusion in cats of different age groups. | |
| | |
MedLine Citation:
|
PMID: 7210069 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Thirty-one cats were divided by age into 3 groups, young (Y), middle (M) and old (O). Continuous recordings of local cerebral blood volume (CBV) and frequent measurements of mean transit time of blood (t) were made from the Sylvian opercula after ischemia was produced by transorbital clipping of the middle cerebral artery at its origin (MCA occlusion). Control recordings were made simultaneously from the corresponding area of the contralateral cerebral hemisphere. MCA occlusion temporarily stopped cerebral blood flow (CBF) in the area supplied by the ipsilateral MCA, as indicated by a rapidly decreasing CBV and complete disappearance of hemodilution curves. Within 30 sec, CBF resumed with a dilatation of the vascular bed and reappearance of hemodilution curves through newly developed collateral channels. Despite a low CBF, below half the control, CBV recovered, overshooting the control level. The appearance of hyperemia in the ischemic area was statistically significant. Such "low perfusion hyperemia" was slower in appearance and of more diverse magnitude in group O than in group Y. This suggested that aging may lead to a decrease in rapidity of the vascular response to ischemia and impair the integrity of collateral vessels. |
| | |
Authors:
|
M Tomita; F Gotoh; T Amano; N Tanahashi; K Tanaka |
Related Documents
:
|
11692029 - Effects of recombinant tissue plasminogen activator after intraluminal thread occlusion... 9555009 - Diffusion, perfusion, and t2 magnetic resonance imaging of anti-intercellular adhesion ... 11739819 - Diffusion-perfusion mri characterization of post-recanalization hyperperfusion in humans. 15196969 - The time course of ischemic damage and cerebral perfusion in a rat model of space-occup... 10688419 - Single lacunar brain infarction with transient signs versus those with long-lasting signs. 10100209 - The significance of hypothermic acid-base management induced before ischemia in a rat m... 15715679 - Pathogen inactivation technology: cleansing the blood supply. 15652469 - Collaterals through hepatic sinusoids after embolization of terminal portal venules: an... 8950589 - Isovolemic hemodilution increases retinal tissue oxygen tension. |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Stroke; a journal of cerebral circulation Volume: 11 ISSN: 0039-2499 ISO Abbreviation: Stroke Publication Date: 1980 Nov-Dec |
Date Detail:
|
Created Date: 1981-05-21 Completed Date: 1981-05-21 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0235266 Medline TA: Stroke Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 629-36 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Age Factors Animals Blood Volume Brain Ischemia / physiopathology* Cats Cerebral Arteries Cerebrovascular Circulation* Collateral Circulation* Constriction Female Hyperemia / etiology* Male Regional Blood Flow Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Histochemical changes of brain dopamine in an acute stage of cerebral ischemia in gerbils.
Next Document: Central conduction time in primate brain ischemia -- a study in baboons.