Document Detail

Low-molecular-weight heparins for the prevention and treatment of venous thromboembolism in at-risk pregnant women: a review.
MedLine Citation:
PMID:  18839817     Owner:  NLM     Status:  MEDLINE    
Certain pregnant populations are at high risk of developing venous thromboembolism (VTE) during pregnancy. Patients at particularly high risk of VTE are those with a history of VTE, thrombophilia or adverse pregnancy outcomes or with mechanical heart valves. In these high-risk patients, evidence-based guidelines recommend the use of thromboprophylaxis. Low-molecular-weight heparin (LMWH) is a safe and effective thromboprophylaxis option in these patients and has a number of administrative and pharmacokinetic advantages over unfractionated heparin. Furthermore, LMWH has also been shown to be a safe and effective treatment for confirmed deep vein thrombosis in pregnant women.
Adam J Duhl
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  53     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-10-08     Completed Date:  2009-02-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  657-66     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Mercy Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.
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MeSH Terms
Anticoagulants / therapeutic use*
Clinical Trials as Topic
Heparin, Low-Molecular-Weight / therapeutic use*
Pregnancy Complications, Hematologic / prevention & control*
Pregnancy, High-Risk*
Venous Thromboembolism / prevention & control*
Reg. No./Substance:
0/Anticoagulants; 0/Heparin, Low-Molecular-Weight

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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