Document Detail

Low-molecular-weight heparins in acute unstable coronary artery disease - an update.
MedLine Citation:
PMID:  10629408     Owner:  NLM     Status:  MEDLINE    
Low-molecular-weight heparins (LMWHs) have been rigorously evaluated in the management of acute coronary ischaemia. The results of clinical trials suggest that the LMWHs (enoxaparin, dalteparin and nadroparin) are effective and safe in the treatment of unstable angina and non-Q-wave myocardial infarction. Two studies have shown enoxaparin to be more effective than unfractionated heparin in this setting. Furthermore, the pharmacologic and pharmacokinetic characteristics of LMWHs result in them having practical and economic advantages. Data on the benefits of long-term therapy with LMWHs are conflicting.
A G Turpie
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Haemostasis     Volume:  29 Suppl S1     ISSN:  0301-0147     ISO Abbreviation:  Haemostasis     Publication Date:  1999 Dec 
Date Detail:
Created Date:  2000-02-25     Completed Date:  2000-02-25     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0371574     Medline TA:  Haemostasis     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  72-5     Citation Subset:  IM    
Copyright Information:
Copyright 1999 S. Karger AG, Basel
Department of Medicine, McMaster University, Hamilton, Ont., Canada.
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MeSH Terms
Angina, Unstable / drug therapy*
Anticoagulants / therapeutic use*
Heparin, Low-Molecular-Weight / therapeutic use*
Reg. No./Substance:
0/Anticoagulants; 0/Heparin, Low-Molecular-Weight

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