Document Detail

Low iodine intake during pregnancy: Relationship to placental development and head circumference in newborn.
MedLine Citation:
PMID:  22381147     Owner:  NLM     Status:  Publisher    
INTRODUCTION: Iodine is considered to be an essential micronutrient in pregnant women. Iodine placental transport to the embryo-fetus is essential for hormone synthesis and is crucial for nervous system development. However, the relationship between iodine intake and placental weight and its potential implications for the newborn have not been studied. MATERIAL AND METHODS: Iodine intake was analyzed in 77 pregnant women based on urinary iodine excretion (UIE) levels, measured using Pinós modified method (normal value, ≥ 150μg/L). Placental weight was measured (PW: normal, ≥500g). In the newborn, weight, height, and head perimeter (HP) were also measured. Placental index (PI: placental weight/newborn weight) was calculated, and was considered normal if ≥0.15. RESULTS: UIE was normal in 50 pregnant women (mean±SD, 279μg/L±70.22μg/L) and decreased in 27 (94μg/L±31.49μg/L). Newborns of mothers with low UIE had a similar weight (3357g±416.30g; n: 27) to those of mothers with normal UIE (3489g±560.59g; n: 50). Forty-four percent of mothers with low UIE had PW <500g, and statistically lower HPs were found in newborns of mothers with low PW (PW(3)500g: 36.05cm±0.55cm, n: 54; PW <500g: 33.93cm±15cm, n:23, p<0.019). Similar results were found with PI, but they did not reach statistical significance (0,17±0,04; p=0.066). No differences were seen in all other parameters. CONCLUSION: The study suggests the existence of a relationship between PW and HP. This finding may be related to iodine intake during pregnancy.
Jorge Luis Olivares; Graciela Inés Olivi; Carina Verdasco; Valeria Analia Ortiz; Marcos Alejandro Mayer; Juan Carlos Cresto
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-28
Journal Detail:
Title:  Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion     Volume:  -     ISSN:  1579-2021     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-3-2     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100886482     Medline TA:  Endocrinol Nutr     Country:  -    
Other Details:
Languages:  ENG; SPA     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 SEEN. Published by Elsevier Espana. All rights reserved.
Facultad de Ciencias Exactas y Naturales y Servicios de Endocrinología y Diabetes, Hospital de Niños R. Gutiérrez, Ciudad de Buenos Aires, Argentina.
Vernacular Title:
Baja ingesta de yodo durante la gestación: Relación con el desarrollo placentario y el perímetro cefálico del recién nacido.
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