Document Detail


Low-intensity magnetic fields assisted alignment of actin filaments.
MedLine Citation:
PMID:  20600267     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This article represents the effects on actin filaments attached to magnetic nanoparticles when exposed to low-intensity magnetic field. In this approach, streptavidin functionalized magnetic nanoparticles were used to demonstrate the alignment of actin filament under external magnetic field of 22mT. To check the directionality of myosin on magnetically aligned actin filaments in vitro motility assay was performed with myosin and average velocity was found to be 3.50microm/s. It was observed that myosin moves in the direction in which actin filaments were magnetically aligned. This approach will explore the capability of integrating molecular motor into microelectronics mechanical system (MEMS) and nanoelectro-mechanical system (NEMS).
Authors:
Harsimran Kaur; Suresh Kumar; Inderpreet Kaur; Kashmir Singh; Lalit M Bharadwaj
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-06-23
Journal Detail:
Title:  International journal of biological macromolecules     Volume:  47     ISSN:  1879-0003     ISO Abbreviation:  Int. J. Biol. Macromol.     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-08-06     Completed Date:  2011-01-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7909578     Medline TA:  Int J Biol Macromol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  371-4     Citation Subset:  IM    
Affiliation:
Biomolecular Electronics and Nanotechnology Division (BEND), Central Scientific Instruments Organization (CSIO), Council of Scientific and Industrial Research (CSIR), Sector-30 C, Chandigarh, India. microsimbac@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Animals
Electronics
Magnetics*
Microfilaments / chemistry*
Nanoparticles / chemistry
Nanotechnology
Particle Size
Rabbits

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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