| Low injection rate for 3D moving-table bolus-chase MR angiography: initial experience with 3-T imaging to allay venous contamination in the calf. | |
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MedLine Citation:
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PMID: 19020244 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The purpose of this study was to evaluate the potential for improving the image quality of 3D bolus-chase peripheral MR angiography by injecting contrast medium at a slow rate. SUBJECTS AND METHODS: Using similar imaging parameters in all cases, we performed bolus-chase MR angiography of the abdominal and lower limb arteries of 80 patients. The injection protocol for 40 patients had three parts: 20 mL of gadopentetate dimeglumine at 2 mL/s, 8 mL of gadopentetate dimeglumine at 1 mL/s, and 20 mL of saline solution at 1 mL/s. For the other 40 patients, the injection protocol was 20 mL of gadopentetate dimeglumine at 1.2 mL/s, 8 mL of gadopentetate dimeglumine at 0.7 mL/s, and 20 mL of saline solution at 0.7 mL/s. Using independent Student's t tests between groups, we compared signal-to-noise and contrast-to-noise ratios in the abdomen and pelvis, the thigh, and the calf. Arterial visibility and venous contamination on 3D images of the calf were graded and compared. RESULTS: The lower injection rate increased arterial visibility (p < 0.001), reduced venous contamination in the calf (p < 0.001), and increased the contrast-to-noise ratio in the calf (p < 0.001). At the upper levels, signal-to-noise and contrast-to-noise ratios did not differ between the two groups. CONCLUSION: At 3-T MRI, a lower injection rate may alleviate venous contamination and increase arterial visibility in the calf while signal-to-noise and contrast-to-noise ratios at higher levels are maintained. |
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Authors:
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Kai Lin; Zhao-Qi Zhang; Jun-Yan Sun; Zhan-Ming Fan; Biao Lu |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: AJR. American journal of roentgenology Volume: 191 ISSN: 1546-3141 ISO Abbreviation: AJR Am J Roentgenol Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2008-11-21 Completed Date: 2009-01-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: United States |
Other Details:
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Languages: eng Pagination: 1734-9 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, Beijing Institute of Heart, Lung, and Blood Vessel Diseases and Beijing Anzhen Hospital, Capital Medical University, Beijing, China. kai@jhmi.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Arterial Occlusive Diseases / diagnosis* Contrast Media / administration & dosage Extravasation of Diagnostic and Therapeutic Materials / prevention & control Female Gadolinium DTPA / administration & dosage*, diagnostic use* Humans Image Enhancement / methods* Injections, Intravenous Leg / blood supply, pathology Magnetic Resonance Angiography / methods* Male Middle Aged Peripheral Vascular Diseases / diagnosis* Pilot Projects Reproducibility of Results Sensitivity and Specificity Veins / pathology |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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