Document Detail


Low-grade malignant eccrine spiradenoma with systemic metastases.
MedLine Citation:
PMID:  12775989     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Malignant eccrine spiradenoma (MES) is a very rare tumor. Tumors can be low grade or high grade. There are nine cases in the literature with systemic metastases. Of these, only one was low grade; the others had obvious features of high-grade malignancy such as pleomorphism, increased mitoses, and abnormal mitoses. Low grade MESs are more difficult to diagnose and are said to have a better prognosis. We report an additional case of low-grade MES with systemic metastases. It had a monotonous appearance with few mitotic figures and minimal pleomorphism. Vascular invasion was seen in both cases of low-grade MES and may be an important prognostic feature.
Authors:
Niamh Leonard; David Smith; Paul McNamara
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  The American Journal of dermatopathology     Volume:  25     ISSN:  0193-1091     ISO Abbreviation:  Am J Dermatopathol     Publication Date:  2003 Jun 
Date Detail:
Created Date:  2003-05-30     Completed Date:  2003-10-07     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7911005     Medline TA:  Am J Dermatopathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  253-5     Citation Subset:  IM    
Affiliation:
Department of Histopathology, Royal Victoria Infirmary, Newcastle-upon-Tyne, England, UK. niamh.leonard@rlbuh-tr.nwest.nhs.uk
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / secondary*,  surgery
Adenoma, Sweat Gland* / pathology,  surgery
Biopsy
Bone Neoplasms / secondary*
Fatal Outcome
Female
Humans
Middle Aged
Neoplasm Metastasis
Sweat Gland Neoplasms / pathology*,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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