Document Detail


Low-grade astrocytoma: surgical outcomes in eloquent versus non-eloquent brain areas.
MedLine Citation:
PMID:  23288019     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A retrospective study of 81 patients with low-grade astrocytoma (LGA) comparing the efficacy of aggressive versus less aggressive surgery in eloquent and non-eloquent brain areas was conducted. Extent of surgical resection was analyzed to assess overall survival (OS) and progression- free survival (PFS). Degree of tumor resection was classified as gross total resection (GTR), subtotal resection (STR) or biopsy. GTR, STR and biopsy in patients with tumors in non-eloquent areas were performed in 31, 48 and 21% subjects, whereas in patients with tumors in eloquent areas resections were 22.5, 35 and 42.5%. Overall survival was 4.7 and 1.9 years in patients with tumors in non-eloquent brain areas submitted to GTR/STR and biopsy (p=0.013), whereas overall survival among patients with tumors in eloquent area was 4.5 and 2.1 years (p=0.33). Improved outcome for adult patients with LGA is predicted by more aggressive surgery in both eloquent and non-eloquent brain areas.
Authors:
André de Macedo Bianco; Flavio Key Miura; Carlos Clara; Jose Reynaldo W Almeida; Clemar Correa da Silva; Manoel Jacobsen Teixeira; Suely K Nagahashi Marie
Related Documents :
24497999 - Neoadjuvant chemotherapy followed by surgery versus surgery alone for gastric carcinoma...
22058419 - Erlotinib for pretreated squamous cell carcinoma of the lung in japanese patients.
23187849 - Postresection surveillance for pancreatic cancer performance status, imaging, and serum...
20172149 - Transition from mediastinoscopy to endoscopic ultrasound for lung cancer staging.
22196919 - Targeted agents in non-small cell lung cancer (nsclc): clinical developments and ration...
16398809 - Complete resection via medial sternotomy for non-small cell lung cancer in the right up...
9696359 - Lc: clinical syndrome in different primaries.
7763039 - Results of the primary treatment in t1-3m0 prostatic adenocarcinoma are dependent on tu...
7515649 - Chlorambucil/prednisone vs. chop in symptomatic low-grade non-hodgkin's lymphomas: a ra...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-08
Journal Detail:
Title:  Arquivos de neuro-psiquiatria     Volume:  -     ISSN:  1678-4227     ISO Abbreviation:  Arq Neuropsiquiatr     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0125444     Medline TA:  Arq Neuropsiquiatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Department of Neurology, Universidade de São Paulo, São Paulo, SP, Brazil.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Outcome correlation of smear-positivity for acid-fast bacilli at the fifth month of treatment in non...
Next Document:  Stroke caused auditory attention deficits in children.