| Low frequency of Toll-like receptors 2 and 4 gene polymorphisms in Mexican patients and their association with Type 2 diabetes. | |
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MedLine Citation:
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PMID: 21902816 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Type 2 diabetes (T2D) is characterized by a chronic low-grade inflammatory state. SNP in Toll-like receptor (TLR) genes has been associated with impaired inflammatory response. We genotyped the TLR4/D299G, TLR4/T399I and TLR2/R753Q polymorphisms. Low frequency was found with no association with T2D, nevertheless the TLR2 SNP was associated with lower levels in HDL-cholesterol values. |
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Authors:
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C Maldonado-Bernal; A Trejo-de la O; M E Sánchez-Contreras; N Wacher-Rodarte; J Torres; M Cruz |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-9 |
Journal Detail:
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Title: International journal of immunogenetics Volume: - ISSN: 1744-313X ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-9 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101232337 Medline TA: Int J Immunogenet Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 Blackwell Publishing Ltd. |
Affiliation:
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Infectious Diseases Research Unit, Hospital de Pediatría, Centro Médico Nacional SXXI, IMSS, México City, México Oncological Diseases Research Unit, Hospital Infantil de México, Federico Gómez, Mexico City, México Biochemistry Research Unit, Hospital de Especialidades, Centro Médico Nacional SXXI, IMSS, México City, México Clinical Epidemiology Research Unit, Hospital de Especialidades, Centro Médico Nacional SXXI, IMSS, México City, México. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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