Document Detail

Low fetal risks in pregnancies associated with idiopathic thrombocytopenic purpura.
MedLine Citation:
PMID:  2101589     Owner:  NLM     Status:  MEDLINE    
Idiopathic thrombocytopenic purpura and pregnancy are commonly associated. In this article we describe our experience in the management of 61 infants born to 50 mothers with confirmed idiopathic thrombocytopenic purpura. The focus was the neonatal cord platelet count, the parameter of greatest interest to obstetricians. None of the 61 infants had morbidity or mortality as a consequence of the thrombocytopenia. Only three of 61 infants (4.9%) had a cord platelet count that was less than 50 x 10(9) per liter. Although 66% of the infants had a further fall in the platelet count after birth, in all the thrombocytopenia could readily be corrected. Neither maternal platelet count, maternal treatment with corticosteroids, maternal platelet-associated immunoglobulin G level, nor maternal splenectomy could be used to predict neonatal thrombocytopenia. Fetal scalp platelet sampling was likely to lead to an erroneous decision. The rareness of a poor neonatal outcome raises the question of whether obstetric interventions are justified for every pregnant patient with idiopathic thrombocytopenic purpura.
R F Burrows; J G Kelton
Related Documents :
11477969 - Every death counts: measurement of maternal mortality via a census.
8041199 - Recognition of maternal identity in preterm and fullterm mothers.
16343339 - National estimates for maternal mortality: an analysis based on the who systematic revi...
9775499 - Perinatal candidiasis and transient maternal candidemia: report of one case.
10946559 - Regulation of mineral and trace elements in human milk: exogenous and endogenous factors.
11476779 - Lactational amenorrhea/anovulation and some of their determinants: a comparison of well...
2371179 - Hyaline membranes in postmature infants.
16375769 - Cloxacillin versus vancomycin for presumed late-onset sepsis in the neonatal intensive ...
24421709 - Clinical problem-solving: short bowel syndrome in an infant.
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  163     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1990 Oct 
Date Detail:
Created Date:  1990-11-16     Completed Date:  1990-11-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1147-50     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, McMaster University Medical Centre, Hamilton, Ontario, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Fetal Blood / cytology
Fetal Diseases / diagnosis,  etiology*
Infant, Newborn
Platelet Count
Pregnancy Complications, Hematologic* / diagnosis
Purpura, Thrombocytopenic* / diagnosis
Retrospective Studies
Risk Factors
Comment In:
Am J Obstet Gynecol. 1991 May;164(5 Pt 1):1362-3   [PMID:  2035582 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A 21-year experience with major hemorrhage after percutaneous liver biopsy.
Next Document:  The probability of obtaining compatible blood from related directed donors.