Document Detail


Low fetal risks in pregnancies associated with idiopathic thrombocytopenic purpura.
MedLine Citation:
PMID:  2101589     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Idiopathic thrombocytopenic purpura and pregnancy are commonly associated. In this article we describe our experience in the management of 61 infants born to 50 mothers with confirmed idiopathic thrombocytopenic purpura. The focus was the neonatal cord platelet count, the parameter of greatest interest to obstetricians. None of the 61 infants had morbidity or mortality as a consequence of the thrombocytopenia. Only three of 61 infants (4.9%) had a cord platelet count that was less than 50 x 10(9) per liter. Although 66% of the infants had a further fall in the platelet count after birth, in all the thrombocytopenia could readily be corrected. Neither maternal platelet count, maternal treatment with corticosteroids, maternal platelet-associated immunoglobulin G level, nor maternal splenectomy could be used to predict neonatal thrombocytopenia. Fetal scalp platelet sampling was likely to lead to an erroneous decision. The rareness of a poor neonatal outcome raises the question of whether obstetric interventions are justified for every pregnant patient with idiopathic thrombocytopenic purpura.
Authors:
R F Burrows; J G Kelton
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  163     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1990 Oct 
Date Detail:
Created Date:  1990-11-16     Completed Date:  1990-11-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1147-50     Citation Subset:  AIM; IM    
Affiliation:
Department of Obstetrics and Gynecology, McMaster University Medical Centre, Hamilton, Ontario, Canada.
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MeSH Terms
Descriptor/Qualifier:
Female
Fetal Blood / cytology
Fetal Diseases / diagnosis,  etiology*
Humans
Infant, Newborn
Platelet Count
Pregnancy
Pregnancy Complications, Hematologic* / diagnosis
Prognosis
Purpura, Thrombocytopenic* / diagnosis
Retrospective Studies
Risk Factors
Comments/Corrections
Comment In:
Am J Obstet Gynecol. 1991 May;164(5 Pt 1):1362-3   [PMID:  2035582 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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