Document Detail

Low drug doses may improve outcomes in chronic disease.
MedLine Citation:
PMID:  19883348     Owner:  NLM     Status:  MEDLINE    
The relationship between drug dose and clinical outcome has not been established for many medications used to treat chronic disease. Evidence is emerging that chronic diseases can be treated effectively with low doses. Adverse drug reactions account for significant morbidity and mortality and are generally dose related. Optimal drug dose - the best balance of benefit and risk - varies between individuals and may change over time. When treating chronic disease it is important to establish and maintain the optimal dose for each patient by close clinical monitoring.
Simon B Dimmitt; Hans G Stampfer
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Publication Detail:
Type:  Editorial    
Journal Detail:
Title:  The Medical journal of Australia     Volume:  191     ISSN:  0025-729X     ISO Abbreviation:  Med. J. Aust.     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-11-03     Completed Date:  2009-12-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0400714     Medline TA:  Med J Aust     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  511-3     Citation Subset:  IM    
University of Western Australia, Perth, WA, Australia.
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MeSH Terms
Chronic Disease / drug therapy*
Drug Administration Schedule
Physician's Practice Patterns

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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