| Low-dose prospective ECG-triggering dual-source CT angiography in infants and children with complex congenital heart disease: first experience. | |
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MedLine Citation:
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PMID: 20532783 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To explore the clinical value of low-dose prospective ECG-triggering dual-source CT (DSCT) angiography in infants and children with complex congenital heart disease (CHD) compared with transthoracic echocardiography (TTE). METHODS: Thirty-five patients (mean age: 16 months, range: 2 months to 6 years; male 15; mean weight: 12 kg) underwent low-dose prospective ECG-triggering DSCT angiography and TTE. Surgeries were performed in 29 patients, and conventional cardiac angiography (CCA) was performed in 8 patients. The accuracy was calculated based on the surgical and/or CCA findings. The overall imaging quality was evaluated on a five-point scale. RESULTS: A total of 146 separate cardiovascular deformities were confirmed. DSCT missed three atrial septal defects and a patent ductus arteriosus. The accuracy of DSCT angiography and TTE was 97.3% (142/146) and 92.5% (135/146), respectively. Overall test parameters for DSCT angiography and TTE were similar (sensitivity, 97.3% vs 92.5%; specificity, 99.8% vs 99.8%). The average subjective image quality score was 4.3 ± 0.7. The mean effective dose was 0.38 ± 0.09 mSv. CONCLUSIONS: Prospective ECG-triggering DSCT angiography with a very low effective radiation dose allows the accurate diagnosis of anomalies in infants and children with complex CHD compared with TTE. It has great promise to become a commonly used second-line technique for complex CHD. |
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Authors:
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Zhaoping Cheng; Ximing Wang; Yanhua Duan; Lebin Wu; Dawei Wu; Baoting Chao; Cheng Liu; Zhuodong Xu; Hongxin Li; Fei Liang; Jian Xu; Jiuhong Chen |
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Publication Detail:
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Type: Journal Article Date: 2010-06-09 |
Journal Detail:
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Title: European radiology Volume: 20 ISSN: 1432-1084 ISO Abbreviation: Eur Radiol Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-09-16 Completed Date: 2011-01-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9114774 Medline TA: Eur Radiol Country: Germany |
Other Details:
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Languages: eng Pagination: 2503-11 Citation Subset: IM |
Affiliation:
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Shandong Medical Imaging Research Institute, Shandong University, No.324, Jingwu Road, Jinan, Shandong, 250021, China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Child Child, Preschool Coronary Angiography / methods* Echocardiography / methods Electrocardiography / methods* Female Heart Diseases / congenital*, radiography Humans Image Processing, Computer-Assisted Infant Male Observer Variation Prospective Studies Radiation Dosage Tomography, X-Ray Computed / methods |
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