Document Detail

Low-dose oral tri-iodothyronine does not directly increase food intake in man.
MedLine Citation:
PMID:  17391172     Owner:  NLM     Status:  MEDLINE    
Previously, we have shown that low-dose tri-iodothyronine (T3) increases food intake in rodents. This randomised, double-blind, placebo-controlled study aimed to investigate the effects of low-dose T3 on food intake in normal body weight individuals. However, despite an elevation in fT3 comparable to our earlier studies, administration of low-dose T3 in the fasted state did not stimulate food intake in man.
N M Martin; C J Small; J L Lee; S Ellis; W S Dhillo; K L Smith; W M Kong; G S Frost; S R Bloom
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Diabetes, obesity & metabolism     Volume:  9     ISSN:  1462-8902     ISO Abbreviation:  Diabetes Obes Metab     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-03-29     Completed Date:  2007-06-22     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  100883645     Medline TA:  Diabetes Obes Metab     Country:  England    
Other Details:
Languages:  eng     Pagination:  435-7     Citation Subset:  IM    
Department of Metabolic Medicine, Hammersmith Hospital, Imperial College London, London, UK.
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MeSH Terms
Administration, Oral
Cross-Over Studies
Double-Blind Method
Eating / drug effects*,  physiology
Energy Intake / physiology
Energy Metabolism / physiology
Thyrotropin / blood
Triiodothyronine / administration & dosage*,  blood
Reg. No./Substance:
6893-02-3/Triiodothyronine; 9002-71-5/Thyrotropin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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