Document Detail

Low-dose multislice CT and high-resolution CT assessment of pulmonary emphysema in public school teachers.
MedLine Citation:
PMID:  17294335     Owner:  NLM     Status:  MEDLINE    
Although rates of emphysematous change in smokers have previously been reported, the precise effects of smoking on emphysematous change have yet to be established because the study subjects of previous reports were heterogeneous in background, and particularly in their professions. This study was prospectively designed to determine the incidence of emphysematous change identified by low-dose multislice computed tomography (LMCT) as well as high-resolution CT (HRCT) imaging in public school teachers. We prospectively examined a series of 859 public school teachers (all males, age = 31-61 years) who had undergone LMCT and HRCT scanning during healthcare examinations. In addition, the subjects' replies to a questionnaire concerning smoking were also collected. Furthermore, most underwent a pulmonary function test. Of the 859 subjects, emphysematous change was found by LMCT imaging in 54 subjects and by HRCT in 75 subjects. All of these subjects were smokers. The FEV(1)/FVC and FEV(1)% predicted were significantly lower for subjects with PE compared with those for subjects without PE. Our study clearly demonstrated the incidence of emphysematous change in smokers in accordance with age.
Noriaki Horiuchi; Jiro Fujita; Ichizo Suemitsu; Yasuhiro Yamasaki; Futoshi Higa; Masao Tateyama
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Publication Detail:
Type:  Journal Article     Date:  2007-02-09
Journal Detail:
Title:  Lung     Volume:  185     ISSN:  0341-2040     ISO Abbreviation:  Lung     Publication Date:    2007 Jan-Feb
Date Detail:
Created Date:  2007-02-20     Completed Date:  2007-04-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7701875     Medline TA:  Lung     Country:  United States    
Other Details:
Languages:  eng     Pagination:  25-30     Citation Subset:  IM    
Department of Internal Medicine, Health Insurance Naruto Hospital, Tokushima, Japan.
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MeSH Terms
Age Factors
Japan / epidemiology
Middle Aged
Prospective Studies
Pulmonary Emphysema / diagnosis,  epidemiology,  radiography*
Respiratory Function Tests
Smoking / adverse effects
Tomography, X-Ray Computed / methods*

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