Document Detail

Low-dose minocycline therapy in tetracycline-recalcitrant acne vulgaris.
MedLine Citation:
PMID:  146595     Owner:  NLM     Status:  MEDLINE    
Ninety-one patients with acne vulgaris were selected for a two-part study primarily because the severity of disease suggested that it might be tetracycline-recalcitrant. Of the eighty-eight patients completing the first part of the study, thirty-two were judged to have tetracycline-nonresponsive acne and received 50 mg of minocycline twice daily for the next six to eight weeks. Twenty-five patients completed this second part of the study. Of these twenty-five, twenty-two experienced a 33 percent or greater reduction in the number of lesions. It is concluded that minocycline in a dosage of 50 mg twice daily is a safe and effective antibiotic for those patients with tetracycline-recalcitrant acne vulgaris.
S I Cullen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cutis     Volume:  21     ISSN:  0011-4162     ISO Abbreviation:  Cutis     Publication Date:  1978 Jan 
Date Detail:
Created Date:  1978-04-17     Completed Date:  1978-04-17     Revised Date:  2013-09-12    
Medline Journal Info:
Nlm Unique ID:  0006440     Medline TA:  Cutis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  101-4     Citation Subset:  IM    
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MeSH Terms
Acne Vulgaris / drug therapy*
Drug Resistance
Minocycline / administration & dosage*,  therapeutic use
Tetracycline / therapeutic use*
Tetracyclines / administration & dosage*
Reg. No./Substance:
0/Tetracyclines; 10118-90-8/Minocycline; 60-54-8/Tetracycline

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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