| Low-dose minocycline therapy in tetracycline-recalcitrant acne vulgaris. | |
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MedLine Citation:
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PMID: 146595 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Ninety-one patients with acne vulgaris were selected for a two-part study primarily because the severity of disease suggested that it might be tetracycline-recalcitrant. Of the eighty-eight patients completing the first part of the study, thirty-two were judged to have tetracycline-nonresponsive acne and received 50 mg of minocycline twice daily for the next six to eight weeks. Twenty-five patients completed this second part of the study. Of these twenty-five, twenty-two experienced a 33 percent or greater reduction in the number of lesions. It is concluded that minocycline in a dosage of 50 mg twice daily is a safe and effective antibiotic for those patients with tetracycline-recalcitrant acne vulgaris. |
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Authors:
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S I Cullen |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Cutis; cutaneous medicine for the practitioner Volume: 21 ISSN: 0011-4162 ISO Abbreviation: Cutis Publication Date: 1978 Jan |
Date Detail:
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Created Date: 1978-04-17 Completed Date: 1978-04-17 Revised Date: 2009-11-11 |
Medline Journal Info:
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Nlm Unique ID: 0006440 Medline TA: Cutis Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 101-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acne Vulgaris
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drug therapy* Adult Drug Resistance Female Humans Minocycline / administration & dosage*, therapeutic use Tetracycline / therapeutic use* Tetracyclines / administration & dosage* |
| Chemical | |
Reg. No./Substance:
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0/Tetracyclines; 10118-90-8/Minocycline; 60-54-8/Tetracycline |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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