| Low-dose arachidonic acid intake increases erythrocytes and plasma arachidonic acid in young women. | |
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MedLine Citation:
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PMID: 20580541 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Arachidonic acid (ARA) is considered to be a minor contributor to the diet. Previous reports regarding the effect of ARA supplementation on the composition of long-chain polyunsaturated fatty acids (LCPUFA) in the blood of humans are extremely limited. In the present study, we conducted a crossover double-blind, placebo-control study. Twenty-three young Japanese women consumed one capsule containing triacylglycerol enriched with 80 mg ARA, equivalent to the amount in one egg, daily for 3 weeks. Blood samples were drawn before and after treatment periods, and the compositions of the LCPUFA in blood lipid fractions were measured. The supplementation of ARA increased the composition of ARA, but did not decrease the composition of n-3LCPUFA in erythrocyte phospholipids and plasma phospholipids, esterified cholesterol, and triacylglycerol. We found that dietary ARA increased the ARA level in all lipid fractions of the blood, even at a very low dose. |
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Authors:
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Satoko Hirota; Naoko Adachi; Toshiharu Gomyo; Hiroshi Kawashima; Yoshinobu Kiso; Terue Kawabata |
Publication Detail:
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Type: Journal Article; Randomized Controlled Trial Date: 2010-06-26 |
Journal Detail:
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Title: Prostaglandins, leukotrienes, and essential fatty acids Volume: 83 ISSN: 1532-2823 ISO Abbreviation: Prostaglandins Leukot. Essent. Fatty Acids Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-08-06 Completed Date: 2010-09-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8802730 Medline TA: Prostaglandins Leukot Essent Fatty Acids Country: Scotland |
Other Details:
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Languages: eng Pagination: 83-8 Citation Subset: IM |
Copyright Information:
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(c) 2010 Elsevier Ltd. All rights reserved. |
Affiliation:
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Kagawa Nutrition University, 3-9-21 Chiyoda, Sakado, Saitama 350-0288, Japan. hirotast@eiyo.ac.jp |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Arachidonic Acid / administration & dosage*, pharmacokinetics* Asian Continental Ancestry Group Cross-Over Studies Dietary Supplements* Double-Blind Method Erythrocytes / metabolism* Fatty Acids, Unsaturated / blood* Female Humans Japan Lipids / blood Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids, Unsaturated; 0/Lipids; 506-32-1/Arachidonic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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