Document Detail

Low-dose amino acid supplementation: no effects on serum human growth hormone and insulin in male weightlifters.
MedLine Citation:
PMID:  8220394     Owner:  NLM     Status:  MEDLINE    
Using a double-blind, crossover protocol, we studied the possible effects of a 4-day combined L-arginine, L-ornithine, and L-lysine supplementation (each 2 g/day, divided into two daily doses) on 24-hr level of serum human growth hormone (hGH) and insulin in 11 competitive weightlifters, ages 19 to 35 yrs. Three similar daily hGH peaks, seemingly preceded by a decrease in serum insulin concentration, were found during both amino acid and placebo supplementation. Supplementation did not affect the physiological variation of serum hGH concentration (treatment and treatment x time interaction: p = 0.43-0.55). Analogously, serum insulin levels were not higher after amino acid supplementation. Therefore the ergogenic value of low-dose oral amino acid supplementation in increasing hGH or insulin secretion seems questionable.
G M Fogelholm; H K Näveri; K T Kiilavuori; M H Härkönen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of sport nutrition     Volume:  3     ISSN:  1050-1606     ISO Abbreviation:  Int J Sport Nutr     Publication Date:  1993 Sep 
Date Detail:
Created Date:  1993-12-06     Completed Date:  1993-12-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9307702     Medline TA:  Int J Sport Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  290-7     Citation Subset:  IM    
Dept. of Applied Chemistry and Microbiology, University of Helsinki, Finland.
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MeSH Terms
Amino Acids / administration & dosage,  pharmacology*
Double-Blind Method
Drug Administration Schedule
Growth Hormone / blood,  drug effects*
Insulin / metabolism
Weight Lifting / physiology*
Reg. No./Substance:
0/Amino Acids; 11061-68-0/Insulin; 9002-72-6/Growth Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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