Document Detail


Low-dose UVA1 phototherapy for proximal and acral scleroderma in systemic sclerosis.
MedLine Citation:
PMID:  19438995     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Previous studies report the benefit of UVA1 phototherapy in treating acrosclerosis in patients with systemic sclerosis. We carried out a retrospective study to examine the effectiveness of UVA1 phototherapy in scleroderma affecting acral and proximal sites in patients with this disease. Patients with systemic sclerosis (diffuse type, n=5; limited type, n=3) underwent low-dose UVA1 radiation (30-40 J/cm(2)) thrice weekly. In all patients skin lesions improved, demonstrated by a fall in the modified Rodnan skin score ranging from 8 to 18 points in diffuse systemic sclerosis and 6 to 10 points in limited disease. This study would suggest that UVA1 phototherapy is effective for scleroderma affecting proximal and acral sites in patients with systemic sclerosis.
Authors:
Rebecca F Rose; David Turner; Mark J D Goodfield; Victoria Goulden
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Photodermatology, photoimmunology & photomedicine     Volume:  25     ISSN:  1600-0781     ISO Abbreviation:  Photodermatol Photoimmunol Photomed     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-05-14     Completed Date:  2009-08-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9013641     Medline TA:  Photodermatol Photoimmunol Photomed     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  153-5     Citation Subset:  IM    
Affiliation:
Department of Dermatology, The General Infirmary at Leeds, Leeds, UK. beckyrose@doctors.org.uk
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Dose-Response Relationship, Radiation
Humans
Middle Aged
Phototherapy*
Scleroderma, Localized / therapy*
Scleroderma, Systemic / therapy*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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