Document Detail


Low-density lipoprotein apheresis therapy during pregnancy.
MedLine Citation:
PMID:  11074223     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Pregnancy in patients with severe hypercholesterolemia and coronary artery disease results in multiple problems both for mother and fetus; the most potent agents for low-density lipoprotein (LDL) cholesterol reduction, the HMG-CoA reductase inhibitors (statins) cannot be used during pregnancy. We present a case in which LDL apheresis via heparin-induced extracorporeal LDL precipitation was employed safely and efficaciously during pregnancy in a woman with heterozygous familial hypercholesterolemia and stable coronary artery disease.
Authors:
L Cashin-Hemphill; M Noone; J F Abbott; C A Waksmonski; R S Lees
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  86     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2000 Nov 
Date Detail:
Created Date:  2000-12-06     Completed Date:  2000-12-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1160, A10     Citation Subset:  AIM; IM    
Affiliation:
Boston Heart Foundation and Harvard/MIT, Cambridge, Massachusetts 02142, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Component Removal / methods*
Cholesterol, LDL / blood*
Coronary Disease / etiology
Female
Humans
Hyperlipoproteinemia Type II / blood*,  complications,  therapy*
Labor, Induced
Myocardial Infarction / etiology
Pregnancy
Pregnancy Complications, Cardiovascular / blood*,  therapy*
Pregnancy Outcome
Treatment Outcome
Chemical
Reg. No./Substance:
0/Cholesterol, LDL
Comments/Corrections
Comment In:
Am J Cardiol. 2001 Jul 15;88(2):202-3   [PMID:  11463060 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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