| Low-density lipoprotein apheresis in the treatment of atherosclerosis and other potential uses. | |
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MedLine Citation:
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PMID: 11177660 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This review concerns the clinical impact of low-density lipoprotein (LDL) apheresis for patients with refractory hypercholesterolemia. We examine and provide examples of investigations that have demonstrated the clinical benefits of LDL apheresis. In addition to benefits derived from the stabilization or regression of arterial lesions, we highlight other possible mechanisms related to clinical improvement. We also discuss the potential advantages of lipid apheresis for the treatment of patient populations other than those characterized by severe hypercholesterolemia and premature coronary heart disease. |
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Authors:
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P M Moriarty; C A Gibson |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Current atherosclerosis reports Volume: 3 ISSN: 1523-3804 ISO Abbreviation: Curr Atheroscler Rep Publication Date: 2001 Mar |
Date Detail:
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Created Date: 2001-02-22 Completed Date: 2001-05-10 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100897685 Medline TA: Curr Atheroscler Rep Country: United States |
Other Details:
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Languages: eng Pagination: 156-62 Citation Subset: IM |
Affiliation:
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Lipid, Atherosclerosis, and Metabolic Clinic, University of Kansas Medical Center, 1336 KU Hospital, 3901 Rainbow Boulevard, Kansas City, KS 66160-7374, USA. pmoriart@kumc.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Blood Component Removal
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methods* Clinical Trials as Topic Coronary Artery Disease / etiology*, therapy* Diabetic Nephropathies / therapy Female Graft Rejection / prevention & control Hearing Loss, Sudden / therapy Heart Transplantation Humans Hypercholesterolemia / complications*, diagnosis Lipoproteins, LDL* Male Particle Size Prognosis Risk Assessment Sensitivity and Specificity Sepsis / therapy Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Lipoproteins, LDL |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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