Document Detail


Low-density lipoprotein apheresis in the treatment of atherosclerosis and other potential uses.
MedLine Citation:
PMID:  11177660     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This review concerns the clinical impact of low-density lipoprotein (LDL) apheresis for patients with refractory hypercholesterolemia. We examine and provide examples of investigations that have demonstrated the clinical benefits of LDL apheresis. In addition to benefits derived from the stabilization or regression of arterial lesions, we highlight other possible mechanisms related to clinical improvement. We also discuss the potential advantages of lipid apheresis for the treatment of patient populations other than those characterized by severe hypercholesterolemia and premature coronary heart disease.
Authors:
P M Moriarty; C A Gibson
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current atherosclerosis reports     Volume:  3     ISSN:  1523-3804     ISO Abbreviation:  Curr Atheroscler Rep     Publication Date:  2001 Mar 
Date Detail:
Created Date:  2001-02-22     Completed Date:  2001-05-10     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  100897685     Medline TA:  Curr Atheroscler Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  156-62     Citation Subset:  IM    
Affiliation:
Lipid, Atherosclerosis, and Metabolic Clinic, University of Kansas Medical Center, 1336 KU Hospital, 3901 Rainbow Boulevard, Kansas City, KS 66160-7374, USA. pmoriart@kumc.edu
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MeSH Terms
Descriptor/Qualifier:
Blood Component Removal / methods*
Clinical Trials as Topic
Coronary Artery Disease / etiology*,  therapy*
Diabetic Nephropathies / therapy
Female
Graft Rejection / prevention & control
Hearing Loss, Sudden / therapy
Heart Transplantation
Humans
Hypercholesterolemia / complications*,  diagnosis
Lipoproteins, LDL*
Male
Particle Size
Prognosis
Risk Assessment
Sensitivity and Specificity
Sepsis / therapy
Treatment Outcome
Chemical
Reg. No./Substance:
0/Lipoproteins, LDL

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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