Document Detail

Low birth weight and fetal anaemia as risk factors for infant morbidity in rural Malawi.
MedLine Citation:
PMID:  20345008     Owner:  NLM     Status:  MEDLINE    
Low birth weight (LBW) and fetal anaemia (FA) are common in malaria endemic areas. To investigate the incidence of infectious morbidity in infants in rural Malawi in relation to birth weight and fetal anaemia, a cohort of babies was followed for a year on the basis of LBW (<2500) and FA (cord haemoglobin < 12.5 g/dl). A matched group of normal birth weight (NBW), non-anaemic (NFA) new-borns were enrolled as controls. Morbidity episodes were recorded at 4-weekly intervals and at each extra visit made to a health centre with any illness. Infants in the NBW NFA group experienced an average of 1.15 (95% C.I. 0.99, 1.31), 1.04 (0.89, 1.19), 0.92 (0.73, 1.11) episodes per year of malaria, respiratory infection and diarrhoea respectively. Corresponding values for the LBW FA group were 0.83 (0.5, 1.16), 0.82 (0.5, 1.16) and 0.76 (0.33, 1.19). FA was not associated with a higher incidence of morbidity, but was significantly associated with a shorter time to first illness episode (p = 0.014). LBW was not a significant risk factor for higher morbidity incidence. LBW and FA were not significant risk factors for incidence of illness episodes in infants.
Boniface Kalanda; Francine Verhoeff; Saskia le Cessie; John Brabin
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Malawi medical journal : the journal of Medical Association of Malawi     Volume:  21     ISSN:  1995-7262     ISO Abbreviation:  Malawi Med J     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2010-03-29     Completed Date:  2010-04-06     Revised Date:  2013-07-25    
Medline Journal Info:
Nlm Unique ID:  9500170     Medline TA:  Malawi Med J     Country:  Malawi    
Other Details:
Languages:  eng     Pagination:  69-74     Citation Subset:  IM    
Child and Reproductive Health Group, Liverpool School of Tropical Medicine, Liverpool, United Kingdom.
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MeSH Terms
Anemia / blood*,  congenital
Fetal Diseases / epidemiology*
HIV Infections / blood,  complications,  epidemiology
Infant, Low Birth Weight*
Infant, Newborn
Malaria, Falciparum / blood,  complications,  epidemiology*
Malawi / epidemiology
Pregnancy Complications, Parasitic / blood,  epidemiology*
Risk Factors
Rural Population

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