Document Detail

Low biochemical nutritional parameters in acutely ill hospitalized elderly patients with and without stage III to IV pressure ulcers.
MedLine Citation:
PMID:  12602578     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND AIMS: Pressure ulcers are associated with impaired nutritional status in acutely ill elderly patients. The objective of this study was to establish whether a difference exists between biochemical nutritional parameters in acutely ill elderly with stage III to IV pressure ulcers and a group of acutely ill elderly with no pressure ulcers. METHODS: In a retrospective study we compared 8 biochemical nutritional markers in a group of 22 acutely ill elderly patients consecutively admitted to the geriatric ward who had stage III to IV pressure ulcers (PU group) in addition to their acute illness with a control group of 40 acutely ill elderly patients with no pressure ulcers (NPU group). RESULTS: The PU group compared with the NPU group had significantly lower (p < 0.0001) values of albumin, transferrin, hemoglobin, cholesterol, iron, and zinc (p < 0.0059). Total lymphocyte count was slightly, but not significantly lower in the PU group. In contrast, C-Reactive Protein levels were significantly higher (p < 0.0001) in the PU group compared with the NPU group, indicating a more severe illness in the presence of additional pressure ulcers. CONCLUSIONS: In this study, serum levels of biochemical nutritional parameters in acutely ill elderly patients with stage III to IV pressure ulcers are lower than those of acutely ill elderly subjects with no pressure ulcers, indicating a worse nutritional status of the PU patients. These findings, while not documenting a causal relationship, suggest the need for routine nutritional assessment and support in older patients, especially those with pressure ulcers.
Michael Gengenbacher; Hannes B Stähelin; André Scholer; Walter O Seiler
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Aging clinical and experimental research     Volume:  14     ISSN:  1594-0667     ISO Abbreviation:  Aging Clin Exp Res     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2003-02-26     Completed Date:  2003-08-05     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  101132995     Medline TA:  Aging Clin Exp Res     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  420-3     Citation Subset:  IM    
Geriatric University Clinic, Clinical Chemical Laboratory, Kantonsspital, Basel, Switzerland.
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MeSH Terms
Acute Disease
Aged, 80 and over
C-Reactive Protein / metabolism
Cholesterol / blood
Geriatric Assessment*
Iron / blood
Middle Aged
Nutrition Assessment*
Nutrition Disorders / blood,  diagnosis*
Pressure Ulcer / blood,  diagnosis*
Retrospective Studies
Serum Albumin
Transferrin / metabolism
Zinc / blood
Reg. No./Substance:
0/Hemoglobins; 0/Serum Albumin; 11096-37-0/Transferrin; 57-88-5/Cholesterol; 7439-89-6/Iron; 7440-66-6/Zinc; 9007-41-4/C-Reactive Protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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