| Low vitamin D levels in Northern American adults with the metabolic syndrome. | |
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MedLine Citation:
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PMID: 21110290 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Metabolic syndrome (MetS), is a constellation of cardiometabolic disease risk factors, that affects 1 in 3 US adults and predisposes to increased risks for both diabetes and cardiovascular disease. While epidemiological studies show low vitamin D [(25(OH)D] levels in MetS, there is sparse data on vitamin D status in MetS patients in North America. Thus, the aim of our study was to examine plasma vitamin D concentration among adults with MetS in Northern California (sunny climate), but without diabetes or cardiovascular disease. 25(OH)D levels were significantly decreased in MetS compared to controls. 8 % of controls and 30% of MetS North American adult subjects were deficient in 25(OH)D (<20 ng/ml; p=0.0236, Controls vs. MetS). There were no significant differences between the groups with respect to blood sampling in winter and summer months, total calcium and phosphate, and creatinine levels. Vitamin D levels were significantly inversely correlated with fasting glucose (r=-0.29, p=0.04) and HOMA (r=-0.34, p=0.04). Future studies of vitamin D supplementation in these subjects on subsequent risk of diabetes will prove instructive with respect to potential health claims in these high risk patients with MetS. |
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Authors:
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S Devaraj; G Jialal; T Cook; D Siegel; I Jialal |
Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't Date: 2010-11-25 |
Journal Detail:
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Title: Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme Volume: 43 ISSN: 1439-4286 ISO Abbreviation: Horm. Metab. Res. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-01-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0177722 Medline TA: Horm Metab Res Country: Germany |
Other Details:
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Languages: eng Pagination: 72-4 Citation Subset: IM |
Copyright Information:
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© Georg Thieme Verlag KG Stuttgart · New York. |
Affiliation:
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Department of Pathology and Laboratory Medicine, University of California, Davis, Sacramento, CA 95817, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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| Grant Support | |
ID/Acronym/Agency:
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K24 AT00596/AT/NCCAM NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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