Document Detail

Low-level laser therapy in the treatment of mucous membrane pemphigoid: a promising procedure.
MedLine Citation:
PMID:  20450370     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Mucous membrane pemphigoid is a heterogeneous group of autoimmune, subepithelial, blistering diseases. A combination of topical and systemic steroid treatment is often used when managing patients with mucous membrane pemphigoid. The use of systemic steroids presents an increased risk of adverse side effects. Consequently, effective alternative modalities of therapy should be considered, such as the application of low-level laser therapy (LLLT).
METHODS: A patient presented with mucous membrane pemphigoid and was successfully treated with the application of local corticosteroids and LLLT using an 810-nm diode laser. The lesions were treated by LLLT over a period of 7 days using a continuous waveform for 40 seconds and an energy density of 5 J/cm(2).
RESULTS: After treatment, a significant improvement in tissue color and consistency was observed. The patient was followed every month for a period of 12 months, and the lesions healed uneventfully.
CONCLUSION: The results reported in this case show that the healing of mucous membrane pemphigoid was achieved when LLLT was used as an adjunct to the application of a local corticosteroid.
Hasan Guney Yilmaz; Basak Kusakci-Seker; Hakan Bayindir; Tolga Fikret Tözüm
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of periodontology     Volume:  81     ISSN:  1943-3670     ISO Abbreviation:  J. Periodontol.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-08-02     Completed Date:  2010-12-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8000345     Medline TA:  J Periodontol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1226-30     Citation Subset:  D; IM    
Department of Periodontology, Faculty of Dentistry, Near East University, Mersin, Turkey.
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MeSH Terms
Anti-Inflammatory Agents / therapeutic use
Betamethasone 17-Valerate / therapeutic use
Follow-Up Studies
Gingival Diseases / drug therapy,  radiotherapy*
Glucocorticoids / therapeutic use
Laser Therapy, Low-Level*
Lasers, Semiconductor / therapeutic use*
Middle Aged
Pemphigoid, Benign Mucous Membrane / drug therapy,  radiotherapy*
Treatment Outcome
Triamcinolone Acetonide / therapeutic use
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Glucocorticoids; 0/Ointments; 2152-44-5/Betamethasone 17-Valerate; 76-25-5/Triamcinolone Acetonide

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