| Low-dose, time-resolved, contrast-enhanced 3D MR angiography in the assessment of the abdominal aorta and its major branches at 3 Tesla. | |
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MedLine Citation:
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PMID: 20171907 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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RATIONALE AND OBJECTIVES: The aims of this study were to evaluate the effectiveness of low-dose, contrast-enhanced (CE), time-resolved, three-dimensional magnetic resonance angiography (MRA) in the assessment of the abdominal aorta and its major branches at 3 T and to compare the results with those of high-spatial resolution CE MRA. MATERIALS AND METHODS: Twenty-two consecutive patients (eight men, 14 women; mean age, 43.9 +/- 17.9 years) underwent CE time-resolved three-dimensional MRA and high-spatial resolution three-dimensional MRA. Studies were performed using a 3-T magnetic resonance system; gadolinium-based contrast medium was administered at a dose of 3 to 5 mL for time-resolved MRA, followed by 0.1 mmol/kg gadopentetate dimeglumine for single-phase CE MRA. For analysis purposes, the abdominal arterial system was divided into 11 arterial segments, and image quality as well as the presence and degree of vascular pathology were evaluated by two independent magnetic resonance radiologists. RESULTS: A total of 242 arterial segments were visualized with good image quality. Time-resolved MRA was able to visualize the majority of arterial segments with good definition in the diagnostic range. Vascular pathologies (stenosis, occlusion) or abnormal vascular anatomy was detected in 19 arterial segments, with good interobserver agreement (kappa = 0.78). All image findings were detected with time-resolved CE MRA by both observers and were confirmed by correlative imaging. CONCLUSION: Low-dose, time-resolved MRA at 3 T yields rapid and important anatomic and functional information in the evaluation of the abdominal vasculature. Because of its limited spatial resolution, time-resolved MRA is inferior to CE MRA in demonstrating fine vascular details. |
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Authors:
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Ulrich Kramer; Michael Fenchel; Gerhard Laub; Achim Seeger; Bernhard Klumpp; Christiane Bretschneider; J Paul Finn; Claus D Claussen; Stephan Miller |
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Publication Detail:
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Type: Journal Article Date: 2010-02-20 |
Journal Detail:
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Title: Academic radiology Volume: 17 ISSN: 1878-4046 ISO Abbreviation: Acad Radiol Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-04-12 Completed Date: 2010-07-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9440159 Medline TA: Acad Radiol Country: United States |
Other Details:
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Languages: eng Pagination: 564-76 Citation Subset: IM |
Copyright Information:
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Copyright 2010 AUR. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Diagnostic and Interventional Radiology, University of Tübingen, Tübingen, Germany. ulrich.kramer@med.uni-tuebingen.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aorta, Abdominal / pathology* Contrast Media / administration & dosage Dose-Response Relationship, Drug Dose-Response Relationship, Radiation Female Gadolinium DTPA / administration & dosage*, diagnostic use* Humans Image Enhancement / methods* Imaging, Three-Dimensional / methods* Magnetic Resonance Angiography / methods* Male Middle Aged Radiation Dosage Reproducibility of Results Sensitivity and Specificity Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 80529-93-7/Gadolinium DTPA |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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