| Loss of circadian blood pressure variability in complete tetraplegia. | |
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MedLine Citation:
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PMID: 8817405 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Blood pressure (BP) and heart rate (HR) were monitored over 24 h utilising an ambulatory blood pressure monitoring (ABPM) system in 33 subjects with spinal cord injury: 11 patients with complete tetraplegia, 13 patients with incomplete tetraplegia and nine patients with complete paraplegia. Measurements were analysed for overall levels of BP and HR, presence of a physiological day/night cycle and events of autonomic dysreflexia. Paraplegic patients exhibited normal BP and HR levels with a physiological circadian rhythm. In complete tetraplegic patients the circadian rhythm was abolished for BP but preserved for HR, while in patients with incomplete tetraplegia circadian rhythm was preserved for both BP and HR. Complete tetraplegic patients with autonomic dysreflexia revealed a typical pattern in ABPM with multiple hypertensive episodes and concomitant bradycardia. Under adequate treatment these episodes could be reduced or abolished, while the disturbed circadian BP rhythm persisted. These observations shed further light on mechanisms of central BP and HR control. In tetraplegic patients ABPM is an efficient method to assess treatment for autonomic dysreflexia. |
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Authors:
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B Nitsche; H Perschak; A Curt; V Dietz |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of human hypertension Volume: 10 ISSN: 0950-9240 ISO Abbreviation: J Hum Hypertens Publication Date: 1996 May |
Date Detail:
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Created Date: 1996-12-10 Completed Date: 1996-12-10 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8811625 Medline TA: J Hum Hypertens Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 311-7 Citation Subset: IM |
Affiliation:
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Swiss Paraplegic Centre, University Hospital Balgrist, Zürich, Switzerland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Autonomic Nervous System / physiopathology Blood Pressure* Blood Pressure Monitoring, Ambulatory Circadian Rhythm* Female Heart Rate Humans Male Middle Aged Neurologic Examination Paraplegia / physiopathology Quadriplegia / physiopathology* Reflex, Abnormal Spinal Cord Injuries / physiopathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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