| Loss of the Y chromosome in a cultured human salivary-gland adenocarcinoma. | |
MedLine Citation:
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PMID: 6418867 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Using in vitro methods, the G-banding pattern in a highly differentiated adenocarcinoma of the parotid gland is described. Results from two consecutive preparations of the carcinoma indicated that it had originated with a normal diploid stemline and, subsequently, during progression had developed an aneuploid stemline deviating from the normal only by loss of the Y chromosome. From this hypodiploid stemline some clones and variant cells had been generated, all of them characterized by numerical deviations, particularly various trisomies. Important cytogenetic similarities were found between the present adenocarcinoma and other types of salivary gland neoplasms, in particular pleomorphic adenomas. |
Authors:
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G Stenman; J Mark |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of oral pathology Volume: 12 ISSN: 0300-9777 ISO Abbreviation: J. Oral Pathol. Publication Date: 1983 Dec |
Date Detail:
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Created Date: 1984-02-14 Completed Date: 1984-02-14 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0342050 Medline TA: J Oral Pathol Country: DENMARK |
Other Details:
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Languages: eng Pagination: 458-64 Citation Subset: D; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenocarcinoma
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genetics* Aged Chromosome Banding Humans Male Parotid Gland / ultrastructure Parotid Neoplasms / genetics* Sex Chromosome Aberrations / genetics* Y Chromosome / ultrastructure* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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