Document Detail


Losing stem cells in the aged skeletal muscle niche.
MedLine Citation:
PMID:  23277280     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Why stem cell numbers decline with age is a major question in regenerative biology and medicine. Skeletal muscle has emerged as a powerful paradigm to address this issue. Recently, genetic and cell marking strategies were used to uncover a new and causal relationship between muscle stem cells and differentiated fibers that constitute their niche and provoke their loss.
Authors:
Shahragim Tajbakhsh
Publication Detail:
Type:  Comment; Journal Article; Research Support, Non-U.S. Gov't     Date:  2013-01-01
Journal Detail:
Title:  Cell research     Volume:  23     ISSN:  1748-7838     ISO Abbreviation:  Cell Res.     Publication Date:  2013 Apr 
Date Detail:
Created Date:  2013-04-01     Completed Date:  2013-09-13     Revised Date:  2014-04-01    
Medline Journal Info:
Nlm Unique ID:  9425763     Medline TA:  Cell Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  455-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aging / physiology*
Animals
Cell Cycle*
Muscle Cells / cytology*
Satellite Cells, Skeletal Muscle / cytology*
Stem Cell Niche / physiology*
Comments/Corrections
Comment On:
Nature. 2012 Oct 18;490(7420):355-60   [PMID:  23023126 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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