| Losartan associated anaphylaxis and angioneurotic oedema. | |
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MedLine Citation:
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PMID: 20726206 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A case of anaphylaxis and angioedema induced by angiotensin II receptor blocker (ARB), losartan is reported. A 37 years old hypertensive female presented to the Emergency Department with swelling over the face especially the lips, urticarial rash all over the body, and dyspnoea within an hour of losartan administration. She did not have any previous history of drug allergies. The patient was managed with epinephrine. Although angioneurotic oedema and anaphylaxis are well documented adverse effects of angiotensin converting enzyme (ACE) inhibitors, very few cases of these adverse reactions with ARBs have been reported in medical literature. |
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Authors:
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Syed Faraz Kazim; Muhammad Shahid |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: JPMA. The Journal of the Pakistan Medical Association Volume: 60 ISSN: 0030-9982 ISO Abbreviation: J Pak Med Assoc Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-08-23 Completed Date: 2010-09-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7501162 Medline TA: J Pak Med Assoc Country: Pakistan |
Other Details:
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Languages: eng Pagination: 685-6 Citation Subset: IM |
Affiliation:
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Department of Surgery, Aga Khan University Hospital, Karachi, Pakistan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Anaphylaxis / chemically induced*, drug therapy Angioedema / chemically induced*, drug therapy Antihypertensive Agents / adverse effects*, therapeutic use Epinephrine / therapeutic use Female Humans Hypertension / drug therapy* Losartan / adverse effects*, therapeutic use Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents; 114798-26-4/Losartan; 51-43-4/Epinephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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