Document Detail

Loop electrosurgical excision procedure in Greek patients with vulvar intraepithelial neoplasia.
MedLine Citation:
PMID:  20527238     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The aim of our study was to evaluate the therapeutic effectiveness of loop electrosurgical excision procedure (LEEP) in Greek patients with vulvar intraepithelial neoplasia (VIN). MATERIALS AND METHODS: Between January 2002 and January 2009, 55 women with histologically confirmed VIN usual type were included in our study. For the LEEP procedure we used a high frequency electrosurgical unit with at least 80 W output. The tissue was removed to the second surgical plane. Statistical analyses were performed using the SPSS-13 for Windows. RESULTS: Complete response rate at 12-month follow-up was 100%. Complete response rate at 48 months of follow-up was 80%. Recurrence rate at 48 months of follow-up was 20%. CONCLUSION: LEEP may constitute a valuable excisional method for the treatment of VIN. It provides an interpretable specimen of the whole lesion within a few minutes. It needs a short period of training and has low cost.
E Terzakis; G Androutsopoulos; G Derdelis; D Zygouris; C Grigoriadis; N Apostolikas
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of gynaecological oncology     Volume:  31     ISSN:  0392-2936     ISO Abbreviation:  Eur. J. Gynaecol. Oncol.     Publication Date:  2010  
Date Detail:
Created Date:  2010-06-08     Completed Date:  2010-06-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8100357     Medline TA:  Eur J Gynaecol Oncol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  191-3     Citation Subset:  IM    
2nd Department of Gynaecology, St. Savvas Anticancer-Oncologic Hospital, Athens, Greece.
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MeSH Terms
Carcinoma in Situ / surgery*
Middle Aged
Neoplasm Recurrence, Local / surgery
Treatment Outcome
Vulvar Neoplasms / surgery*

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