Document Detail

Longitudinal study of the health of cotton workers.
MedLine Citation:
PMID:  7795755     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To follow up a group of newly employed workers in a cotton mill, and to report changes in symptoms over time. METHODS: A group of 110 mill workers at a cotton mill in Shijiazhuang, China, was investigated by questionnaire, skin testing, and spirometric measurements of airway responsiveness through forced expiratory volume in one second (FEV1). The workers were examined before starting work, at 10 weeks, and at one year. RESULTS: Decreases in FEV1 over shifts were small at 10 weeks and one year, and slightly higher among people with skin reactions to cotton dust extracts. Airway responsiveness, defined as the average decrease in FEV1 after 1.25 mg methacholine was increased at 10 weeks. It remained about the same after one year, except in the workers positive for the skin test, in whom it was further increased. Subjective symptoms of chest tightness and cough with phlegm increased progressively at 10 weeks and one year; nasal irritation remained unchanged and dry cough decreased between 10 weeks and one year. CONCLUSION: The results suggest that the airway inflammation caused by cotton dust increases with increasing exposure time and that the changes are more notable in workers with reactivity to cotton dust extract.
D Li; Y N Zhong; R Rylander; Q Y Ma; X Y Zhou
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Occupational and environmental medicine     Volume:  52     ISSN:  1351-0711     ISO Abbreviation:  Occup Environ Med     Publication Date:  1995 May 
Date Detail:
Created Date:  1995-07-31     Completed Date:  1995-07-31     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  9422759     Medline TA:  Occup Environ Med     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  328-31     Citation Subset:  IM    
Institute of Occupational Medicine, Beijing, China.
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MeSH Terms
Dust / adverse effects*
Endotoxins / administration & dosage
Follow-Up Studies
Forced Expiratory Volume
Hypersensitivity, Immediate / complications
Intradermal Tests
Methacholine Chloride / diagnostic use
Occupational Diseases / etiology*,  physiopathology
Occupational Exposure / adverse effects
Respiration Disorders / etiology*,  physiopathology
Reg. No./Substance:
0/Dust; 0/Endotoxins; 62-51-1/Methacholine Chloride

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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