Document Detail


Longitudinal respiratory health study of the wood processing industry.
MedLine Citation:
PMID:  18496790     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: A 5-year longitudinal study examined nonmalignant respiratory effects of wood processing dust exposure. METHODS: Ten study plants, investigator selected from 447 candidate plants, included 1 sawmill-planing-plywood, 1 plywood, 1 milling, 3 cabinet and 4 furniture facilities. Personal dust samples (2363) were divided into three size fractions (extrathoracic, tracheobronchial, and respirable) which were apportioned into wood solids (WS) and residual particulate matter (RPM), and used to compute each individuals TWA exposure for the 6 exposure types. Serial spirometric tests and medical, smoking and occupational questionnaires were collected with 1,164 subjects having adequate follow-up (minimum 3 datapoints over at least 2.5 years) for analyses. Forward selection regression was used to evaluate the effect of exposure on annual change in FEV(1), FVC, FEF(25-75), and FEV(1)/FVC. RESULTS: There were no significant adverse effects of WS exposures (overall means were 0.66, 0.32, and 0.05 mg/m(3), for extrathoracic, tracheobronchial, and respirable fractions, respectively). Statistically significant effects were only to respirable RPM in the milling facility (mean exposures of 0.147 mg/m(3) associated with changes in FEV(1) = -32 ml/year, FEV(1)/FVC = -0.48%/year, and FEF(25-75) = -0.11 l/s/year) and in the sawmill-planing-plywood facility (mean exposures of 0.255 mg/m(3) associated with changes in FEV(1) = -59 ml/year and FVC = -103 ml/year). CONCLUSION: Exposure to WS was not associated with significant adverse effects. Respirable RPM was associated with an obstructive effect in the milling facility, and respirable RPM was also associated with a restrictive effect in the sawmill-planing plywood facility. Finally, this study does not exclude the possibility that other exposures common to this industry can cause respiratory effects, only that none were noted in this population for wood solids for the exposure levels and durations studied.
Authors:
Henry W Glindmeyer; Roy J Rando; John J Lefante; Laurie Freyder; Joseph A Brisolara; Robert N Jones
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of industrial medicine     Volume:  51     ISSN:  1097-0274     ISO Abbreviation:  Am. J. Ind. Med.     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-07-17     Completed Date:  2008-08-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8101110     Medline TA:  Am J Ind Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  595-609     Citation Subset:  IM    
Affiliation:
Department of Medicine, School of Medicine, Tulane University Health Sciences Center, New Orleans, Louisiana 70118, USA. hglindmeyer@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Air Pollutants, Occupational / analysis*
Dust / analysis*
Environmental Monitoring*
Female
Health Surveys
Humans
Industry
Longitudinal Studies
Male
Occupational Exposure / analysis
Spirometry
Wood / analysis*
Chemical
Reg. No./Substance:
0/Air Pollutants, Occupational; 0/Dust

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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