Document Detail

Longitudinal reference ranges for estimated fetal weight.
MedLine Citation:
PMID:  16553175     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The aims of the present study were to establish reference ranges for the growth of estimated fetal weight (EFW) between gestational weeks 20 and 42 and to determine the effect of fetal and maternal factors. METHODS: This prospective longitudinal study was based on 634 low-risk pregnancies and a total of 1799 examinations. Gestational age was computed from last menstrual period. Head circumference, abdominal circumference, and femur length were measured using ultrasound, and EFW was calculated using the formula of Combs et al. The statistical analysis was based on regression analysis and multilevel modeling. RESULTS: Intrauterine growth expressed by EFW showed a continuous pattern until term. Males were calculated to be 5% heavier than female fetuses at 20 gestational weeks and 3% at 40 weeks. Otherwise, the fetal and maternal effects on intrauterine growth correspond to a weight shift of 1.3% for breech/nonbreech, 2.5% for each increase in maternal height tertile, and -4% for smoking/nonsmoking. Maternal age higher than 34 years had a significant increased EFW of 4.5% compared with maternal age less than 24 years. Cephalic index in the third tertile had a 1.1% lower EFW compared with the first tertile. Maternal weight, body mass index, and parity did not influence the EFW. Terms for customization to individualize the growth patterns are presented. CONCLUSIONS: The present growth chart is recommended as robust reference ranges for assessing EFW and growth. Fetal and maternal variables can be added into the models to individualize the prediction of EFW.
Synnøve Lian Johnsen; Svein Rasmussen; Tom Wilsgaard; Rita Sollien; Torvid Kiserud
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  85     ISSN:  0001-6349     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  2006  
Date Detail:
Created Date:  2006-03-23     Completed Date:  2006-04-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  286-97     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Haukeland University Hospital, Bergen, Norway.
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MeSH Terms
Birth Weight*
Fetal Development*
Infant, Newborn
Longitudinal Studies
Maternal Age
Models, Theoretical
Pregnancy Trimester, Second
Pregnancy Trimester, Third
Reference Values
Comment In:
Acta Obstet Gynecol Scand. 2006;85(8):1022-3; author reply 1023-4   [PMID:  16862490 ]

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