Document Detail


Longitudinal postnatal weight measurements for the prediction of retinopathy of prematurity.
MedLine Citation:
PMID:  20385939     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To validate longitudinal postnatal weight gain as a method for predicting severe retinopathy of prematurity (ROP) in a US cohort.
METHODS: Both ROP evaluations and weekly weight measurements from birth to postmenstrual week 36 for 318 infants were entered into a computer-based surveillance system, WINROP. This system signaled an alarm when the rate of weight gain decreased compared with control subjects. Infants were classified into 3 groups: (1) no alarm, (2) low-risk alarm, or (3) high-risk alarm. Maximum ROP for each infant was categorized as (1) no ROP (immature or mature vascularization), (2) mild ROP (stage 1 or 2 ROP in zone II or III, without plus disease), or (3) severe ROP (any prethreshold, any stage 3, or threshold ROP). A high-risk alarm identified infants at risk for developing severe ROP.
RESULTS: A high-risk alarm occurred in 81 infants (25.5%) and detected all infants who developed severe ROP a median of 9 weeks before diagnosis. The remaining infants received no alarm or a low-risk alarm. None of these infants developed more than mild ROP.
CONCLUSIONS: Longitudinal postnatal weight gain may help predict ROP. In a US cohort, the WINROP system had a sensitivity of 100% and identified infants early who developed severe ROP. With further validation, WINROP has the potential to safely reduce the number of ROP examinations.
Authors:
Carolyn Wu; Deborah K Vanderveen; Ann Hellström; Chatarina Löfqvist; Lois E H Smith
Related Documents :
20845249 - [vegf antibodies as therapy for retinopathy of prematurity].
16432409 - Anthropometric study of the upper lip and the nose of infants less than a year of age.
16270909 - Palatal development of preterm and low birthweight infants compared to term infants - w...
11150259 - The outcome of retinopathy of prematurity: screening for retinopathy of prematurity usi...
20187739 - Incidence of use of acid suppression medications in infants with oral clefting.
12825059 - Retinopathy of prematurity in infants with birth weights greater than 1250 grams.
7176609 - Mothers' perceptions of infant distress vocalizations.
25251299 - Risk indicators for congenital and delayed-onset hearing loss.
8517899 - Urinary endothelin-1-like immunoreactivity excretion in the newborn period.
Publication Detail:
Type:  Journal Article; Validation Studies    
Journal Detail:
Title:  Archives of ophthalmology     Volume:  128     ISSN:  1538-3601     ISO Abbreviation:  Arch. Ophthalmol.     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-04-13     Completed Date:  2010-05-03     Revised Date:  2014-04-28    
Medline Journal Info:
Nlm Unique ID:  7706534     Medline TA:  Arch Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  443-7     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Algorithms
Birth Weight / physiology*
Female
Gestational Age
Humans
Infant
Infant, Newborn
Infant, Premature
Infant, Very Low Birth Weight
Insulin-Like Growth Factor I / analysis
Longitudinal Studies
Male
Retinopathy of Prematurity / blood,  diagnosis*
Retrospective Studies
Sentinel Surveillance
Weight Gain / physiology*
Chemical
Reg. No./Substance:
67763-96-6/Insulin-Like Growth Factor I

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Correlation between epithelial ingrowth and basement membrane remodeling in human corneas after lase...
Next Document:  In vivo laser-tissue interactions and healing responses from 20- vs 100-millisecond pulse Pascal pho...