| Longitudinal performance of a surgically implanted neuroprosthesis for lower-extremity exercise, standing, and transfers after spinal cord injury. | |
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MedLine Citation:
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PMID: 22541312 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To investigate the longitudinal performance of a surgically implanted neuroprosthesis for lower-extremity exercise, standing, and transfers after spinal cord injury. DESIGN: Case series. SETTING: Research or outpatient physical therapy departments of 4 academic hospitals. PARTICIPANTS: Subjects (N=15) with thoracic or low cervical level spinal cord injuries who had received the 8-channel neuroprosthesis for exercise and standing. INTERVENTION: After completing rehabilitation with the device, the subjects were discharged to unrestricted home use of the system. A series of assessments were performed before discharge and at a follow-up appointment approximately 1 year later. MAIN OUTCOME MEASURES: Neuroprosthesis usage, maximum standing time, body weight support, knee strength, knee fatigue index, electrode stability, and component survivability. RESULTS: Levels of maximum standing time, body weight support, knee strength, and knee fatigue index were not statistically different from discharge to follow-up (P>.05). Additionally, neuroprosthesis usage was consistent with subjects choosing to use the system on approximately half of the days during each monitoring period. Although the number of hours using the neuroprosthesis remained constant, subjects shifted their usage to more functional standing versus more maintenance exercise, suggesting that the subjects incorporated the neuroprosthesis into their lives. Safety and reliability of the system were demonstrated by electrode stability and a high component survivability rate (>90%). CONCLUSIONS: This group of 15 subjects is the largest cohort of implanted lower-extremity neuroprosthetic exercise and standing system users. The safety and efficiency data from this group, and acceptance of the neuroprosthesis as demonstrated by continued usage, indicate that future efforts toward commercialization of a similar device may be warranted. |
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Authors:
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Ronald J Triolo; Stephanie Nogan Bailey; Michael E Miller; Loretta M Rohde; James S Anderson; John A Davis; James J Abbas; Lisa A DiPonio; George P Forrest; David R Gater; Lynda J Yang |
Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: Archives of physical medicine and rehabilitation Volume: 93 ISSN: 1532-821X ISO Abbreviation: Arch Phys Med Rehabil Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-04-30 Completed Date: 2012-07-24 Revised Date: 2013-02-06 |
Medline Journal Info:
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Nlm Unique ID: 2985158R Medline TA: Arch Phys Med Rehabil Country: United States |
Other Details:
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Languages: eng Pagination: 896-904 Citation Subset: AIM; IM |
Copyright Information:
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Copyright © 2012 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Louis Stokes Cleveland Department of Veterans Affairs Medical Center, Cleveland, OH 44106, USA. |
| Data Bank Information | |
Bank Name/Acc. No.:
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ClinicalTrials.gov/NCT00004445 |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Cervical Vertebrae Female Humans Kaplan-Meier Estimate Knee / physiology* Longitudinal Studies Lower Extremity / physiopathology Male Muscle Fatigue Muscle Strength Neural Prostheses* / adverse effects Patient Acceptance of Health Care* Prosthesis Failure Prosthesis Implantation Spinal Cord Injuries / physiopathology*, rehabilitation, surgery Thoracic Vertebrae Time Factors Weight-Bearing / physiology |
| Grant Support | |
ID/Acronym/Agency:
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UL1 RR024989/RR/NCRR NIH HHS; UL1 RR024989/RR/NCRR NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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