Document Detail

Longitudinal myelitis, aseptic meningitis, and conus medullaris infarction as presenting manifestations of pediatric systemic lupus erythematosus.
MedLine Citation:
PMID:  18413416     Owner:  NLM     Status:  MEDLINE    
A healthy boy developed subacutely progressive quadriparesis, complicated by sudden paraplegia, fever, and meningeal signs, diagnosed as longitudinal myelitis, aseptic meningitis, and conus medullaris infarction and identified as the presenting manifestations of neuropsychiatric systemic lupus erythematosus. Rapid expansion of the conus on serial neuroimaging led to emergent decompressive laminectomy and cord biopsy showing vasculitis and cord infarction. The patient had partial recovery after treatment with high-dose steroids. Increased vigilance is required when pediatric patients develop a similar subacute presentation on the ground of active systemic lupus erythematosus because it may herald the onset of a catastrophic neurological syndrome.
A M Katramados; R Rabah; M D Adams; A H M M Huq; P D Mitsias
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Lupus     Volume:  17     ISSN:  0961-2033     ISO Abbreviation:  Lupus     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-04-16     Completed Date:  2008-09-19     Revised Date:  2011-03-11    
Medline Journal Info:
Nlm Unique ID:  9204265     Medline TA:  Lupus     Country:  England    
Other Details:
Languages:  eng     Pagination:  332-6     Citation Subset:  IM    
Department of Neurology, Henry Ford Hospital, Detroit, Michigan 48202, USA.
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MeSH Terms
Follow-Up Studies
Infarction / diagnosis,  etiology*,  surgery
Lupus Erythematosus, Systemic / complications*,  diagnosis
Magnetic Resonance Imaging
Meningitis, Aseptic / diagnosis,  etiology*
Myelitis / diagnosis,  etiology*
Spinal Cord / blood supply*
Spinal Cord Compression / complications*,  diagnosis,  surgery
Thoracic Vertebrae

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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