Document Detail

Longitudinal melanonychia associated with hydroxyurea therapy in a patient with essential thrombocytosis.
MedLine Citation:
PMID:  10568495     Owner:  NLM     Status:  MEDLINE    
Occurrence of skin lesions during long-term therapy with hydroxyurea are well described, but there have been only a few case reports of longitudinal melanonychia associated with hydroxyurea treatment. We report herein longitudinal melanonychia associated with hydroxyurea therapy in a subject with essential thrombocytosis. The prolonged time lapse (1 year) between initiation of hydroxyurea therapy and the onset of the longitudinal melanonychia should be noted.
A D Cohen; D Hallel-Halevy; L Hatskelzon; E Peretz; S Halevy
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the European Academy of Dermatology and Venereology : JEADV     Volume:  13     ISSN:  0926-9959     ISO Abbreviation:  J Eur Acad Dermatol Venereol     Publication Date:  1999 Sep 
Date Detail:
Created Date:  1999-12-02     Completed Date:  1999-12-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9216037     Medline TA:  J Eur Acad Dermatol Venereol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  137-9     Citation Subset:  IM    
Department of Dermatology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
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MeSH Terms
Hydroxyurea / adverse effects*
Melanins / analysis
Melanosis / chemically induced*
Nail Diseases / chemically induced*
Thrombocytosis / drug therapy*
Time Factors
Reg. No./Substance:
0/Melanins; 127-07-1/Hydroxyurea

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