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Longitudinal growth of very low birth weight neonates during first year of life and risk factors for malnutrition in a developing country.
MedLine Citation:
PMID:  23205735     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
AIMS: To study growth of very low birth weight neonates (VLBW) during first year and identify risk factors of malnutrition METHODS: Neonates ≤34 weeks and ≤1500g enrolled in a human milk fortification trial were prospectively followed till one year corrected age. Anthropometry was plotted on WHO charts. Risk factors were compared between well nourished and underweight neonates. RESULTS: 132, 127, 110, 99 and 101 neonates were followed at corrected age of 40 weeks, 3, 6, 9 and 12 months. Weight (Mean Z-score -2.3 ± 1.2 to -1.7 ± 1.4; p=0.005) and length (-2.1 ± 1.5 to -1.5 ± 1.3; p=0.004) improved significantly, while head circumference declined (-0.92 ± 1.1 to -1.2 ± 1.1; p <0.001). Incidence of underweight, stunting, microcephaly and wasting changed from 63%, 53%, 13% and 52% neonates at 40 weeks to 41%, 32%, 21% and 27% at one year. Growth between fortified and unfortified or SGA and AGA groups were similar, while Extremely low birth weight (ELBW) neonates showed poorer growth. Z-score of weight at 3 months emerged as an independent predictor of malnutrition at one year. CONCLUSION: VLBW neonates, especially the ELBW group remained growth retarded at corrected age of one year. Z-score of weight at 3 months was a significant risk factor for malnutrition at one year. ©2012 The Author(s)/Acta Paediatrica ©2012 Foundation Acta Paediatrica.
Authors:
Kanya Mukhopadhyay; Rama Mahajan; Deepak Louis; Anil Narang
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-12-3
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  -     ISSN:  1651-2227     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
©2012 The Author(s)/Acta Paediatrica ©2012 Foundation Acta Paediatrica.
Affiliation:
Neonatal unit, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
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