Document Detail

Longitudinal evaluation of the effect of smoking initiation on body weight, blood pressure, and blood biochemistry.
MedLine Citation:
PMID:  19344738     Owner:  NLM     Status:  In-Process    
OBJECTIVE: To evaluate the effect of smoking initiation on annual changes in body weight, blood pressure, and blood biochemistry. METHODS: This study analyzed the results of annual health examinations from 1991 to 2005 in male Japanese workers. Subjects who started smoking (n=214) initially responded as non-smokers in a self-administered questionnaire (baseline year) and then answered consistently as smokers for 3 subsequent years. Out of 2547 non-smokers, we selected 1589 controls who had data available for at least four successive years. The time course of physiological and laboratory data was analyzed using a linear mixed model. RESULTS: A significant temporal decrease from baseline in body mass index (first year, -0.1 kg/m(2)), diastolic blood pressure (second year, -1.5 mm Hg) and gamma-glutamyl transpeptidase (second year, -3.5 IU/L) was observed for subjects who started smoking. An opposite pattern was observed in non-smokers. On average, those who started smoking had significantly lower body mass index (first year, -0.2 kg/m(2); second year, -0.2 kg/m(2)), systolic blood pressure (second year, -2.1 mm Hg), diastolic blood pressure (second year, -2.0 mm Hg), and gamma-glutamyl transpeptidase (second year, -4.5 IU/L) than non-smokers. CONCLUSION: In this study, smoking initiation did not yield clinically significant long-term benefits with respect to physiological or biochemical outcomes. These results are important because few studies have tracked these types of changes longitudinally from initiation through 3 years of follow-up.
Yumi Kadonaga; Mirei Dochi; Kouichi Sakata; Mitsuhiro Oishi; Kumihiko Tanaka; Hideki Morimoto; Etsuko Kobayashi; Yasushi Suwazono
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-03-31
Journal Detail:
Title:  Preventive medicine     Volume:  48     ISSN:  1096-0260     ISO Abbreviation:  Prev Med     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-06-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0322116     Medline TA:  Prev Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  567-71     Citation Subset:  IM    
Department of Occupational and Environmental Medicine (A2), Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuoku, Chiba, Japan.
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