Document Detail


Longitudinal estimates of pulmonary function decline in grain workers.
MedLine Citation:
PMID:  8087334     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We conducted a cohort analysis of longitudinal changes in pulmonary function test values in male grain elevator workers in five regions of Canada over a 6-yr period involving three observations. Pulmonary function tests were obtained approximately each 3 yr during an observation interval called a "cycle". The periods of the cycles were 1978-81 (Cycle I), 1981-84 (Cycle II), and 1984-87 (Cycle III), respectively. Data on respiratory symptoms and pulmonary function tests were collected on the same 881 workers in Cycles I and II (mean ages +/- SE: 37.0 +/- 0.48 yr at Cycle I), on the same 1,294 workers in Cycles I, II, and III (34.6 +/- 0.34 yr at Cycle I), and on the same 1,021 workers in Cycles II and III (33.9 +/- 0.38 yr at Cycle II) for a total of 3,196 workers with two or more observations over the 6-yr period. The proportion of current smokers decreased from Cycle I to Cycle III. Autoregression analysis of longitudinal changes in lung function data showed that predictors of FEV1 were height, years in the industry, smoking status, and geographic region. The mean annual losses in FEV1 (FVC) were 28.7 ml (26.4 ml), 38.4 ml (41.9 ml), and 41.7 ml (32.3 ml) for nonsmokers, ex-smokers, and current smokers, respectively. The annual loss of FEV1 (FVC) was 9.2 ml (21.1 ml) for those who were in the grain industry for less than 5 yr and 52.6 ml (60.8 ml) for those who were exposed for 20 yr or more.(ABSTRACT TRUNCATED AT 250 WORDS)
Authors:
P Pahwa; A Senthilselvan; H H McDuffie; J A Dosman
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of respiratory and critical care medicine     Volume:  150     ISSN:  1073-449X     ISO Abbreviation:  Am. J. Respir. Crit. Care Med.     Publication Date:  1994 Sep 
Date Detail:
Created Date:  1994-10-20     Completed Date:  1994-10-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9421642     Medline TA:  Am J Respir Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  656-62     Citation Subset:  AIM; IM    
Affiliation:
Centre for Agricultural Medicine, University of Saskatchewan, Saskatoon, Canada.
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MeSH Terms
Descriptor/Qualifier:
Adult
Agricultural Workers' Diseases / epidemiology,  etiology,  physiopathology*
Canada / epidemiology
Cereals / adverse effects*
Dust / adverse effects*
Forced Expiratory Volume
Humans
Longitudinal Studies
Lung / physiopathology*
Male
Middle Aged
Models, Statistical
Regression Analysis
Respiratory Function Tests / statistics & numerical data
Respiratory Tract Diseases / epidemiology,  etiology,  physiopathology*
Smoking / epidemiology,  physiopathology
Time Factors
Chemical
Reg. No./Substance:
0/Dust

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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