| Longitudinal changes in plasma glucose values of the 75-g glucose tolerance test in triplet pregnancies. | |
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MedLine Citation:
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PMID: 15017466 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We evaluated longitudinal changing patterns of 75 g glucose tolerance test (GTT) in triplet pregnancies. Eight triplet pregnancies were prospectively studied. All triplet pregnancies were fertilized with artificial reproductive techniques; patients showed no glucosuria or fasting hyperglycemia > 100 mg/dL before pregnancy. The 75-g GTT was performed at first, second, and third trimester, as well as at postpartum. Longitudinal changes in glucose levels at fasting, 1 hour, and 2 hours were compared by one-way repeated-measure analysis of variance (ANOVA) and Bonferroni/Dunn test ( p < 0.05). Values were expressed as mean +/- standard deviation. Each of the 3-point values of 75-g GTT decreased after 28 weeks of gestation in triplet pregnancies. During the third trimester, fasting values were significantly decreased compared with postpartum values (65.5 +/- 13.4 versus 74.6 +/- 4.0 mg/dL), and 2-hour values were significantly decreased from those of second-trimester 75-g GTT (116.3 +/- 19.5 versus 99.6 +/- 17.1 mg/dL). Longitudinal glucose values of 75-g GTT improve during third trimester in triplet pregnancies, suggesting that fetoplacental fuel drain may counterbalance maternal insulin resistance. |
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Authors:
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Hiroshi Sameshima; Takafumi Higo; Tsuyomu Ikenoue |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: American journal of perinatology Volume: 21 ISSN: 0735-1631 ISO Abbreviation: Am J Perinatol Publication Date: 2004 Feb |
Date Detail:
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Created Date: 2004-03-12 Completed Date: 2004-06-03 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8405212 Medline TA: Am J Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 49-55 Citation Subset: IM |
Affiliation:
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Perinatal Center and Department of Obstetrics and Gynecology, Miyazaki Medical College, Miyazaki, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Glucose / metabolism* Diabetes, Gestational / blood* Female Glucose Tolerance Test Humans Longitudinal Studies Pregnancy Pregnancy Trimesters / blood Pregnancy, Multiple / blood* Prospective Studies Triplets |
| Chemical | |
Reg. No./Substance:
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0/Blood Glucose |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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