Document Detail


Longitudinal changes in plasma glucose values of the 75-g glucose tolerance test in triplet pregnancies.
MedLine Citation:
PMID:  15017466     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We evaluated longitudinal changing patterns of 75 g glucose tolerance test (GTT) in triplet pregnancies. Eight triplet pregnancies were prospectively studied. All triplet pregnancies were fertilized with artificial reproductive techniques; patients showed no glucosuria or fasting hyperglycemia > 100 mg/dL before pregnancy. The 75-g GTT was performed at first, second, and third trimester, as well as at postpartum. Longitudinal changes in glucose levels at fasting, 1 hour, and 2 hours were compared by one-way repeated-measure analysis of variance (ANOVA) and Bonferroni/Dunn test ( p < 0.05). Values were expressed as mean +/- standard deviation. Each of the 3-point values of 75-g GTT decreased after 28 weeks of gestation in triplet pregnancies. During the third trimester, fasting values were significantly decreased compared with postpartum values (65.5 +/- 13.4 versus 74.6 +/- 4.0 mg/dL), and 2-hour values were significantly decreased from those of second-trimester 75-g GTT (116.3 +/- 19.5 versus 99.6 +/- 17.1 mg/dL). Longitudinal glucose values of 75-g GTT improve during third trimester in triplet pregnancies, suggesting that fetoplacental fuel drain may counterbalance maternal insulin resistance.
Authors:
Hiroshi Sameshima; Takafumi Higo; Tsuyomu Ikenoue
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of perinatology     Volume:  21     ISSN:  0735-1631     ISO Abbreviation:  Am J Perinatol     Publication Date:  2004 Feb 
Date Detail:
Created Date:  2004-03-12     Completed Date:  2004-06-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  49-55     Citation Subset:  IM    
Affiliation:
Perinatal Center and Department of Obstetrics and Gynecology, Miyazaki Medical College, Miyazaki, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Glucose / metabolism*
Diabetes, Gestational / blood*
Female
Glucose Tolerance Test
Humans
Longitudinal Studies
Pregnancy
Pregnancy Trimesters / blood
Pregnancy, Multiple / blood*
Prospective Studies
Triplets
Chemical
Reg. No./Substance:
0/Blood Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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