Document Detail

Longitudinal change of treatment-related upper limb dysfunction and its impact on late dysfunction in breast cancer survivors: a prospective cohort study.
MedLine Citation:
PMID:  19924721     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND OBJECTIVES: To investigate the prevalence of upper limb dysfunction (ULD) and subtypes after breast cancer surgery and to identify factors associated with late ULD. METHODS: Among 191 enrolled patients, 191 were evaluated at 3 months, 187 at 6 months, and 183 at 12 months after surgery. Pain, shoulder range of motion, muscle strength, and arm circumference were assessed. Based on symptoms and physical examinations, the types of ULD common after breast cancer treatment were diagnosed and categorized. RESULTS: The prevalence of ULD after surgery were 24.6%, 20.9%, and 26.8% at 3, 6, and 12 months, respectively. The most common types of ULD were pectoralis tightness at 3 and 6 months and lymphedema at 12 months. Patients with pectoralis tightness or lymphedema at 3 or 6 months showed a higher prevalence of rotator cuff disease at 12 months compared with those without early pectoralis tightness or lymphedema. CONCLUSIONS: The major post-operative ULD were pectoralis tightness at 3 and 6 months and lymphedema at 12 months. Late ULD such as rotator cuff disease were associated with pectoral tightness or lymphedema at earlier stages. Diagnosis and treatment of ULD should take place as soon as possible after surgery.
Eun Joo Yang; Won-Beom Park; Kwan Sik Seo; Sung-Won Kim; Chan-Yeong Heo; Jae-Young Lim
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of surgical oncology     Volume:  101     ISSN:  1096-9098     ISO Abbreviation:  J Surg Oncol     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-29     Completed Date:  2010-01-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0222643     Medline TA:  J Surg Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  84-91     Citation Subset:  IM    
Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Gyeonggi-do 463-707, Republic of Korea.
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MeSH Terms
Breast Neoplasms / pathology,  physiopathology,  surgery*
Cohort Studies
Logistic Models
Longitudinal Studies
Lymphedema / epidemiology
Mastectomy / adverse effects*
Mastectomy, Segmental / adverse effects
Middle Aged
Muscle Strength
Postoperative Complications / epidemiology*
Prospective Studies
Range of Motion, Articular
Sentinel Lymph Node Biopsy
Upper Extremity / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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