| Longitudinal brain perfusion changes in near-term small-for-gestational-age fetuses as measured by spectral Doppler indices or by fractional moving blood volume. | |
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MedLine Citation:
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PMID: 20435282 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The objective of this study was to compare the temporal sequence of fetal brain hemodynamic changes in near-term small-for-gestational-age fetuses as measured by spectral Doppler indices or by fractional moving blood volume. STUDY DESIGN: Cerebral tissue perfusion measured by fractional moving blood volume, cerebroplacental ratio, anterior cerebral artery, and middle cerebral artery pulsatility indices were weekly performed in a cohort of singleton consecutive small-for-gestational-age fetuses with normal umbilical artery delivered after 37 weeks of gestation. RESULTS: A total of 307 scans were performed on 110 small-for-gestational-age fetuses. Mean gestational age at diagnosis and at delivery was 35.7 and 38.6 weeks, respectively. The proportion of fetuses with abnormal fractional moving blood volume, cerebroplacental ratio, anterior cerebral artery-pulsatility index, and middle cerebral artery-pulsatility index values was 31.3%, 16.8%, 17.2%, and 10.8% at 37 weeks of gestation and 42.7%, 23.6%, 20.9%, and 16.4% before delivery. CONCLUSION: The presence of brain redistribution in small-for-gestational-age fetuses was detected earlier and in a higher proportion of fetuses using cerebral tissue perfusion rather than spectral Doppler indices. |
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Authors:
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Rogelio Cruz-Martinez; Francesc Figueras; Edgar Hernandez-Andrade; Bienvenido Puerto; Eduard Gratacós |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-05-01 |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 203 ISSN: 1097-6868 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-07-08 Completed Date: 2010-09-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 42.e1-6 Citation Subset: AIM; IM |
Copyright Information:
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Copyright (c) 2010 Mosby, Inc. All rights reserved. |
Affiliation:
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Department of Maternal-Fetal Medicine, Institut Clínic de Ginecologia, Obstetrícia i Neonatologia, University of Barcelona, Barcelona, Spain. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Flow Velocity / physiology Brain / blood supply* Cerebrovascular Circulation / physiology* Cohort Studies Female Humans Infant, Newborn Infant, Small for Gestational Age / physiology* Kaplan-Meiers Estimate Middle Cerebral Artery / physiology, ultrasonography Pregnancy Pregnancy Complications, Cardiovascular / physiopathology*, ultrasonography Prospective Studies Ultrasonography, Doppler |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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