| Longitudinal right ventricular function as a predictor of functional capacity in patients with mitral stenosis: an exercise echocardiographic study. | |
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MedLine Citation:
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PMID: 20434881 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: The influence of right ventricular (RV) function on exercise capacity has been poorly explored in mitral stenosis (MS). The objective of this study was to assess the determinants of functional status with exercise echocardiography in MS. METHODS: Thirty-nine patients (55 +/- 12 years, 29 female) with MS (1.3 +/- 0.5 cm(2)) underwent an exercise echocardiography (14 patients had previous balloon valvuloplasty). RV function was assessed by tricuspid annulus S-wave velocity (Tric-S) and tricuspid annular plane systolic excursion (TAPSE). RESULTS: Tric-S correlated with TAPSE (P = .03), cardiac output (P = .006), and mitral valve area (P = .009). With exercise, Tric-S and TAPSE increased significantly (11.3 +/- 3.1 cm/s to 15.5 +/- 3.4 cm/s and 21.2 +/- 5.2 mm to 24.0 +/- 5.8 mm, respectively, both P < .05). TAPSE was lower in patients in New York Heart Association class 3 or 4. In multivariate analysis, Tric-S at rest (beta = 0.34, P = .006) and mitral Delta mean diastolic gradient (beta = 0.34, P = .006) were the independent determinants of maximum workload. CONCLUSION: Resting RV longitudinal function assessed through Tric-S is an important determinant of functional capacity in MS. |
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Authors:
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Guillaume Deswarte; Marjorie Richardson; Anne Sophie Polge; Sébastien Pouwels; Pierre Vladimir Ennezat; Jean-Noël Trochu; Benoit Wallaert; Ghislaine Deklunder; Thierry Le Tourneau |
Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography Volume: 23 ISSN: 1097-6795 ISO Abbreviation: J Am Soc Echocardiogr Publication Date: 2010 Jun |
Date Detail:
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Created Date: 2010-05-25 Completed Date: 2010-08-20 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8801388 Medline TA: J Am Soc Echocardiogr Country: United States |
Other Details:
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Languages: eng Pagination: 667-72 Citation Subset: IM |
Copyright Information:
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Copyright 2010 American Society of Echocardiography. Published by Mosby, Inc. All rights reserved. |
Affiliation:
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Service d'Explorations Fonctionnelles, Cardiology University Hospital, CHRU, Lille, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Echocardiography, Stress Exercise Tolerance Female Humans Male Middle Aged Mitral Valve Stenosis / physiopathology, therapy, ultrasonography* Ventricular Dysfunction, Right / physiopathology, ultrasonography* Ventricular Function, Right |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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