Document Detail

Longitudinal effect of smoking cessation on physical and laboratory findings.
MedLine Citation:
PMID:  20117576     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Detailed information on the expected physiologic changes after smoking cessation is practically useful to encourage people to stop smoking. Furthermore, weight increase after cessation may affect such physiologic changes. PURPOSE: This article aims to evaluate the effect of smoking cessation on annual changes in body weight, blood pressure, and blood biochemistry. METHODS: This study analyzed the results of annual health examinations from 1991 to 2005 in male Japanese workers in 2009. Subjects classified as stopping smoking (n=445) responded initially as smokers in a self-administered questionnaire (baseline year) and then answered consistently as nonsmokers for 3 subsequent years. Of the 2672 smokers identified in the study, 2403 subjects who had data available for at least 4 successive years were selected as controls. The time course of physiologic and laboratory data was analyzed using a linear mixed model. RESULTS: Data adjusted for age, type of job schedule, drinking and physical activity showed that subjects who stopped smoking had significantly greater increases in weight, BMI, systolic and diastolic blood pressure, total cholesterol, high-density lipoprotein cholesterol, and uric acid and a greater decrease in hemoglobin in the 3 years following smoking cessation than continuing smokers. Additional adjustment for change in BMI from baseline negated the significant deterioration in systolic and diastolic blood pressure and total cholesterol that occurred following smoking cessation. CONCLUSIONS: Increase in body weight, blood pressure, and blood biochemistry can continue for at least 3 years after smoking cessation. This study also indicated that these increases were related to the weight increase that occurred after smoking cessation.
Yasushi Suwazono; Mirei Dochi; Mitsuhiro Oishi; Kumihiko Tanaka; Hideki Morimoto; Kouichi Sakata
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  American journal of preventive medicine     Volume:  38     ISSN:  1873-2607     ISO Abbreviation:  Am J Prev Med     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-02-01     Completed Date:  2010-04-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8704773     Medline TA:  Am J Prev Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  192-200     Citation Subset:  IM    
Copyright Information:
Copyright 2010 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.
Department of Occupational and Environmental Medicine (A2), Graduate School of Medicine, Chiba University, 1-8-1 Inohana, Chuoku, Chiba 260-8670, Japan.
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MeSH Terms
Blood Chemical Analysis*
Blood Pressure / physiology*
Body Weight / physiology*
Longitudinal Studies
Middle Aged
Smoking Cessation*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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